Severe covid-19 pneumonia: pathogenesis and clinical management

AH Attaway, RG Scheraga, A Bhimraj, M Biehl… - bmj, 2021 - bmj.com
Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Prone position in ARDS patients: why, when, how and for whom

C Guérin, RK Albert, J Beitler, L Gattinoni, S Jaber… - Intensive care …, 2020 - Springer
In ARDS patients, the change from supine to prone position generates a more even
distribution of the gas–tissue ratios along the dependent–nondependent axis and a more …

COVID-19 pneumonia: pathophysiology and management

L Gattinoni, S Gattarello, I Steinberg… - European …, 2021 - Eur Respiratory Soc
Coronavirus disease 2019 (COVID-19) pneumonia is an evolving disease. We will focus on
the development of its pathophysiologic characteristics over time, and how these time …

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial

J Rosén, E von Oelreich, D Fors, M Jonsson Fagerlund… - Critical Care, 2021 - Springer
Background The effect of awake prone positioning on intubation rates is not established.
The aim of this trial was to investigate if a protocol for awake prone positioning reduces the …

Coronavirus disease 2019 as cause of viral sepsis: a systematic review and meta-analysis

E Karakike, EJ Giamarellos-Bourboulis… - Critical care …, 2021 - journals.lww.com
Objective: Coronavirus disease 2019 is a heterogeneous disease most frequently causing
respiratory tract infection, which can induce respiratory failure and multiple organ …

Factors for success of awake prone positioning in patients with COVID-19-induced acute hypoxemic respiratory failure: analysis of a randomized controlled trial

M Ibarra-Estrada, J Li, I Pavlov, Y Perez, O Roca… - Critical Care, 2022 - Springer
Background Awake prone positioning (APP) improves oxygenation in coronavirus disease
(COVID-19) patients and, when successful, may decrease the risk of intubation. However …

Effect of prone versus supine position in COVID-19 patients: A systematic review and meta-analysis

EX Chua, SMISM Zahir, KT Ng, WY Teoh… - Journal of Clinical …, 2021 - Elsevier
Study objective To review the effects of prone position and supine position on oxygenation
parameters in patients with Coronavirus Disease 2019 (COVID-19). Design Systematic …

Assessment of awake prone positioning in hospitalized adults with COVID-19: a nonrandomized controlled trial

ET Qian, CL Gatto, O Amusina, ML Dear… - JAMA internal …, 2022 - jamanetwork.com
Importance Awake prone positioning may improve hypoxemia among patients with COVID-
19, but whether it is associated with improved clinical outcomes remains unknown. Objective …

[HTML][HTML] Noninvasive respiratory support and patient self-inflicted lung injury in COVID-19: a narrative review

D Battaglini, C Robba, L Ball, PL Silva, FF Cruz… - British Journal of …, 2021 - Elsevier
COVID-19 pneumonia is associated with hypoxaemic respiratory failure, ranging from mild
to severe. Because of the worldwide shortage of ICU beds, a relatively high number of …

[HTML][HTML] Prone positioning for non-intubated spontaneously breathing patients with acute hypoxaemic respiratory failure: a systematic review and meta-analysis

B Fazzini, A Page, R Pearse, Z Puthucheary - British Journal of …, 2022 - Elsevier
Background Prone positioning in non-intubated spontaneously breathing patients is
becoming widely applied in practice alongside noninvasive respiratory support. This …