Mycolic acids are major and specific lipid components of the mycobacterial cell envelope
and are essential for the survival of members of the genus Mycobacterium that contains the …

Atovaquone belongs to a naphthoquinone class of drugs and is used in combination with
proguanil (Malarone) for the treatment of acute, uncomplicated malaria caused by …

The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …

Background: Naphthoquinones are natural pigments that are widely distributed in nature
and have important biological activities. Lawsone (2-hydroxy-1, 4-naphthoquinone) and its …

Lawsone (1) is a special naphthoquinone that is useful for many applications in various
scientific and technological fields. For over 100 years, it has been used as the starting …

Bacterial resistance development represents a serious threat to human health across the
globe and has become a very serious clinical problem for many classes of antibiotics …

This review involves the chemistry and biochemistry of lapachol, β-lapachone and lawsone,
examples of bioactive natural products that still being under biological evaluation and …

A new chloranilate compound with 1-(2-fluorophenyl) piperazine has been synthesized and
characterized using spectroscopic methods and X-ray diffraction. The atomic arrangement …

The aims of this study were the planning, synthesis and in vitro evaluation of 2-hydroxy-3-
phenylsulfanylmethyl-[1, 4]-naphthoquinones against Gram-negative and Gram-positive …

Malaria is a life threatening disease caused by microscopic parasites called Plasmodium
that are transmitted to human beings by mosquitoes. Single celled Eukaryotic plasmodium …