Neuropathy will afflict over half of the estimated 460 million people worldwide who have
diabetes, 303 of whom approximately onethird will also develop neuropathic pain. 2 The …

Cancer is the quintessential complex disease. As technologies evolve faster each day, we
are able to quantify the different layers of biological elements that contribute to the …

Diabetic peripheral neuropathy (DPN) is one of the most widespread and disabling
neurological conditions, accounting for half of all neuropathy cases worldwide. Despite its …

Dyslipidemia is an emerging mechanism in microvascular complications in T2D. Elucidating
the molecular pathomechanisms may pinpoint potential lipid-centric treatments …

Diabetic neuropathy is a neurodegenerative disorder that may alter both the somatic and
autonomic peripheral nervous systems in the context of diabetes mellitus (DM). It is a …

Metabolism is loosely defined as the set of physical and chemical interactions associated
with the processes responsible for sustaining life. Two evident features arise whenever one …

Neurological diseases are highly prevalent and constitute a significant cause of mortality
and disability. Neurological disorders encompass a heterogeneous group of …

It is widely accepted that molecular reductionist views of highly complex human physiologic
activity, eg, the aging process, as well as therapeutic drug efficacy are largely …

The oncogenesis and progression of thyroid cancer (THCA) involve multiple pathways.
Identification of potential interaction mechanisms of pathways related to the pathogenesis of …

Peripheral neuropathy (PN) is a common complication in patients with metabolic
dysfunction, including obesity, prediabetes, and type 2 diabetes. Standard management …