Dendritic cells (DCs) are the key link between innate immunity and adaptive immunity and
play crucial roles in both the promotion of immune defense and the maintenance of immune …

Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

The skin is the outermost organ of the body and is continuously exposed to external
pathogens. Upon inflammation, various immune cells pass through, reside in or are …

Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and their ability to
migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune …

Lymphatic vessels collect interstitial fluid that has extravasated from blood vessels and
return it to the circulatory system. Another important function of the lymphatic network is to …

Dendritic cells (DCs) are professional antigen-presenting cells responsible for the activation
of specific T-cell responses and for the development of immune tolerance. Immature DCs …

Omega-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid,
docosapentaenoic acid and docosahexaenoic acid, display a wide range of beneficial …

The COVID-19 pandemic has raised international awareness of the importance of rigorous
scientific evidence and the havoc caused by uncontrolled excessive inflammation. Here we …

IgA, previously called Henoch-Schönlein vasculitis, is an essential immune component that
drives the host immune response to the external environment. As IgA has the unique …

CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events
in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph …