Microneedles: materials, fabrication, and biomedical applications

X Luo, L Yang, Y Cui - Biomedical Microdevices, 2023 - Springer
The microneedles have attracted great interests for a wide range of transdermal biomedical
applications, such as biosensing and drug delivery, due to the advantages of being …

Microneedle technology as a new standpoint in agriculture: Treatment and sensing

E Ece, I Eş, F Inci - Materials Today, 2023 - Elsevier
Preventing plant loss and improving their health status are essential for agricultural industry.
Correspondingly, the deprivation of plants severely impacts our ecological system. As such …

Considerations in the use of microneedles: pain, convenience, anxiety and safety

HR Jeong, HS Lee, IJ Choi, JH Park - Journal of drug targeting, 2017 - Taylor & Francis
Transdermal delivery using microneedles is gaining increasing attention from
pharmaceutical and cosmetic companies as one of the promising drug delivery methods …

Design, analysis and fabrication of solid polymer microneedle patch using CO2 laser and polymer molding

G Anbazhagan, SB Suseela… - Drug Delivery and …, 2023 - Springer
Microneedle-based transdermal drug delivery into the skin has gained attraction for the past
few years. An affordable and effective fabrication methodology is required for the …

Microfluidic chip to interface porous microneedles for ISF collection

K Takeuchi, N Takama, B Kim, K Sharma, O Paul… - Biomedical …, 2019 - Springer
Porous microneedles (MNs) are expected to be applied for diagnostic microfluidic devices
such as blood glucose monitoring as they enable a pain-free penetration of human skin and …

Separable microneedles for near-infrared light-triggered transdermal delivery of metformin in diabetic rats

Y Zhang, D Wang, M Gao, B Xu, J Zhu… - ACS Biomaterials …, 2018 - ACS Publications
Near-infrared (NIR) light-triggered and separable segmented microneedles (MNs),
consisting of lauric acid and polycaprolactone (LA/PCL) arrowheads and poly (vinyl alcohol) …

Microneedles for vaccine delivery: challenges and future perspectives

CI Shin, SD Jeong, NS Rejinold, YC Kim - Therapeutic delivery, 2017 - Taylor & Francis
Vaccine delivery to the skin using conventional needles is associated with needle-stick
injuries and needle-phobia, which are all major obstacles to vaccination. The development …

Functionalized microneedles for continuous glucose monitoring

K Takeuchi, B Kim - Nano convergence, 2018 - Springer
Microneedles (MNs) have been established as promising medical devices as they are
minimally invasive, cause less pain, and can be utilized for self-administration of drugs by …

Innovative fabrication of hollow microneedle arrays enabling blood sampling with a self-powered microfluidic patch

L Van Hileghem, S Kushwaha, A Piovesan… - Micromachines, 2023 - mdpi.com
Microneedles are gaining a lot of attention in the context of sampling cutaneous biofluids
such as capillary blood. Their minimal invasiveness and user-friendliness make them a …

Optimizing CNC milling parameters for manufacturing of ultra-sharp tip microneedle with various tip angles

HP Pham, VT Vo, TQ Nguyen - Drug Delivery and Translational Research, 2024 - Springer
Microneedle technology has emerged as an advanced method for transdermal drug
delivery, which focuses on diverse fabrication techniques to develop microneedles with …