Aging in cats: common physical and functional changes

J Bellows, S Center, L Daristotle… - Journal of Feline …, 2016 - journals.sagepub.com
Practical relevance: Aged pets comprise a significant proportion of the small animal
veterinarian's patient population; in the USA, for example, it was estimated that over 20% of …

[HTML][HTML] Spontaneous painful disease in companion animals can facilitate the development of chronic pain therapies for humans

BDX Lascelles, DC Brown, W Maixner… - Osteoarthritis and …, 2018 - Elsevier
Objective To outline the role that spontaneous osteoarthritis (OA) in companion animals can
play in translational research and therapeutic pharmacological development. Outline …

[HTML][HTML] Characterization of osteoarthritis in cats and meloxicam efficacy using objective chronic pain evaluation tools

M Guillot, M Moreau, M Heit, J Martel-Pelletier… - The Veterinary …, 2013 - Elsevier
This study aimed to characterize osteoarthritis (OA)-related chronic pain and disability in
experimental cats with naturally occurring OA. Peak vertical ground reaction force (PVF) …

Feline musculoskeletal pain index: responsiveness and testing of criterion validity

J Benito, B Hansen, V Depuy… - Journal of Veterinary …, 2013 - Wiley Online Library
Background Progress in establishing if therapies provide relief to cats with degenerative
joint disease (DJD)‐associated pain is hampered by a lack of validated owner‐administered …

Criterion validation testing of clinical metrology instruments for measuring degenerative joint disease associated mobility impairment in cats

ME Gruen, EH Griffith, AE Thomson, W Simpson… - PLoS …, 2015 - journals.plos.org
Introduction Degenerative joint disease and associated pain are common in cats,
particularly in older cats. There is a need for treatment options, however evaluation of …

Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats

BDX Lascelles, YH Dong, DJ Marcellin-Little… - BMC veterinary …, 2012 - Springer
Background Available information suggests a mismatch between radiographic and
orthopedic examination findings in cats with DJD. However, the extent of the discrepancy …

Reliability and discriminatory testing of a client-based metrology instrument, feline musculoskeletal pain index (FMPI) for the evaluation of degenerative joint disease …

J Benito, V Depuy, E Hardie, H Zamprogno… - The Veterinary …, 2013 - Elsevier
The objective of this study was to test the readability, reliability, repeatability and
discriminatory ability of an owner-completed instrument to assess feline degenerative joint …

Efficacy and safety of an anti-nerve growth factor antibody (frunevetmab) for the treatment of degenerative joint disease-associated chronic pain in cats: a multisite pilot …

ME Gruen, JAE Myers, BDX Lascelles - Frontiers in veterinary science, 2021 - frontiersin.org
Background: Pain management for cats with degenerative joint disease (DJD) remains a
critical unmet need. Recent work has shown promise for a feline-specific anti-nerve growth …

Owner evaluation of quality of life and mobility in osteoarthritic cats treated with amantadine or placebo

H Shipley, K Flynn, L Tucker… - Journal of Feline …, 2021 - journals.sagepub.com
Objectives The aim of the study was to determine if amantadine improves owner-identified
mobility impairment and quality of life associated with osteoarthritis in cats. Methods Using a …

Evaluation and comparison of pain questionnaires for clinical screening of osteoarthritis in cats

S Stadig, BDX Lascelles, G Nyman… - Veterinary Record, 2019 - Wiley Online Library
Background Feline osteoarthritis (OA) is a common cause of long‐standing pain and
physical dysfunction. Performing a physical examination of a cat is often challenging. There …