Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly with a progressive decline in cognitive function significantly affecting quality of life …

Mild Cognitive Impairment (MCI) is a clinical syndrome characterized by a moderate decline
in one or more cognitive functions with a preserved autonomy in daily life activities. MCI …

Introduction: While amnestic mild cognitive impairment (aMCI) and non-amnestic mild
cognitive impairment (naMCI) are theoretically different entities, only a few investigations …

Introduction Better characterization of the relationship between episodic memory and
hippocampal volumes is crucial in early detection of neurodegenerative disease. We …

One factor believed to impact brain resilience to the pathological damage of Alzheimer's
disease (AD) is the so-called “cognitive reserve”(CR). A critical issue that still needs to be …

Background: Voxel-based morphometry (VBM) has been widely used to investigate
structural alterations in amnesia mild cognitive impairment (aMCI). However, inconsistent …

While mild cognitive impairment (MCI) has been classified into amnestic MCI (aMCI) and
nonamnestic MCI (naMCI), the neuropathological bases of these two subtypes remain …

Amnestic mild cognitive impairment (aMCI) is a prodromal stage of Alzheimer's disease that
is characterized by impairments in episodic memory. Recent evidence has shown that …

Background: HDL-cholesterol transporter Apolipoprotein A1 (ApoA1) holds neuroprotective
properties, such as inhibition of amyloid-β aggregation. Low plasma ApoA1 concentrations …

This longitudinal study investigates the modifications in structure and function occurring to
typical Alzheimer's disease (AD) brains over a 2-year follow-up, from pre-dementia stages of …