The dramatic recent advances in molecular biology, which have opened a new era in
medicine and biotechnology, rely on improved techniques to study large molecules …

During the last decade, capillary electrophoresis (CE) of DNA has undergone rapid
development. This improvement was especially important for DNA sequencing, where CE …

▪ Abstract The Human Genome Project and other major genomic sequencing projects have
pushed the development of sequencing technology. In the past six years alone, instrument …

We present the first example of the analysis of long double-stranded (ds) DNA molecules by
nanoparticle-filled capillary electrophoresis (NFCE). To avoid aggregation of the gold …

DNA is a free‐draining polymer. This subtle but “unfortunate” property of highly charged
polyelectrolytes makes it impossible to separate nucleic acids by free‐flow electrophoresis …

Method and composition for detecting one or more selected polynucleotide regions in a
target polynucleotide. In the method, a mixture of sequence-specific probes are reacted with …

Although electrophoresis is one of the basic methods of the modern molecular biology
laboratory, new ideas are being suggested at an accelerated rate, in large part because of …

The ability to controllably and continuously stretch large DNA molecules in a microfluidic
format is important for gene mapping technologies such as Direct Linear Analysis (DLA). We …

We present in this paper a new Lab-on-Chip (LoC) architecture for dielectrophoresis-based
cell manipulation, detection, and capacitive measurement. The proposed LoC is built around …

DNA sequencing by capillary electrophoresis has been reviewed with an emphasis on
progress during the last four years. The effects of sample purification, composition of sieving …