A newly synthesized thiosemicarbazide derivative trigger apoptosis rather than necroptosis on HEPG2 cell line

F Başoğlu‐Ünal, E Becer, HK Ensarioğlu… - Chemical Biology & …, 2024 - Wiley Online Library
Thiosemicarbazide derivatives have been the focus of scientists owing to their broad
biological activities such as anticancer, antimicrobial, and anti‐inflammatory. Herein, we …

Synthesis, anticancer evaluation, photophysical properties and molecular docking studies of new thiazolyl-thiadiazolyl ketones (D-π-A structured)

A Bayazeed, H Alharbi, AI Alalawy, RB Alnoman… - … of Photochemistry and …, 2024 - Elsevier
A series of thiazolyl-thiadiazolyl ketones 5a and 5b and their corresponding Schiff's bases
6a and 6b were synthesized based on the reaction of 2-(2-amino-4-methylthiazol-5-yl)-N-(4 …

Design, synthesis and molecular modeling studies of thiosemicarbazide & thiazolyl-hydrazone derivatives as potential anticancer agents and topoisomerase inhibitors

S Şenkardeş, İ Bolat, H Şahinbey, S Karakuş… - Journal of Molecular …, 2024 - Elsevier
This study involved the design, synthesis and evaluation of a series of novel
thiosemicarbazide and thiazolyl-hydrazone derivatives. The synthesized compounds were …