Objective We sought to better understand the workflow, outcomes, and complications of
deep brain stimulation (DBS) for pediatric status dystonicus (SD). We present a systematic …

Dystonia is one of the most common pediatric movement disorders and can have a profound
impact on the lives of children and their caregivers. Response to pharmacologic treatment is …

Objective: To report long-term safety and efficacy outcomes of a large cohort of patients with
medically refractory isolated dystonia treated with subthalamic nucleus (STN) deep brain …

Our understanding of the syndromes of Neurodegeneration with Brain Iron Accumulation
(NBIA) continues to grow considerably. In addition to the core syndromes of pantothenate …

Inherited metabolic diseases or inborn errors of metabolism frequently manifest with both
hyperkinetic (dystonia, chorea, myoclonus, ataxia, tremor, etc.) and hypokinetic (rigid …

Abstract When considering Deep Brain Stimulation (DBS) surgical treatment of dystonia
syndromes, it is important to consider multiple aspects of the disease and its presentation. It …

Objective Dystonia in pantothenate kinase-associated neurodegeneration (PKAN) is
progressive despite medication. Deep brain stimulation (DBS) was reported to effectively …

Back arching was reported in one of the very first patients with neurodegeneration with brain
iron accumulation syndrome (NBIAs) published in 1936. However, recent reports have …

Refractory movement disorders are a common feature of inborn errors of metabolism (IEMs),
significantly impacting quality of life and potentially leading to life-threatening complications …

Dystonia is a clinical syndrome of sustained muscle contractions producing twisting and
repetitive movements or abnormal postures, often resulting in simultaneous contraction of …