The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …

The problem of antibiotic resistance among pathogenic bacteria has reached a crisis level.
The treatment options against infections caused by multiple drug-resistant bacteria are …

Monoamine neurotransmitters such as dopamine and serotonin control important brain
pathways, including movement, sleep, reward and mood. Dysfunction of monoaminergic …

Inorganic phosphate (Pi) is a fundamental macronutrient for all living organisms, the
homeostasis of which is critical for numerous biological activities,–. As the only known …

Glycoscience assembles all the scientific disciplines involved in studying various molecules
and macromolecules containing carbohydrates and complex glycans. Such an ensemble …

Abstract Organic Cation Transporter 1 (OCT1) plays a crucial role in hepatic metabolism by
mediating the uptake of a range of metabolites and drugs. Genetic variations can alter the …

Organic cation transporters (OCTs) facilitate the translocation of catecholamines, drugs and
xenobiotics across the plasma membrane in various tissues throughout the human body …

The organic anion transporting polypeptides OATP1B1 and OATP1B3 are membrane
proteins that mediate uptake of drugs into the liver for subsequent conjugation and biliary …

A wide range of endogenous and xenobiotic organic ions require facilitated transport
systems to cross the plasma membrane for their disposition. In mammals, organic cation …

Membrane protein-mediated resistance is a multidisciplinary challenge that spans fields
such as medicine, agriculture, and environmental science. Understanding its complexity and …