Radiation-induced lung injury: assessment and management

AN Hanania, W Mainwaring, YT Ghebre, NA Hanania… - Chest, 2019 - Elsevier
Radiation-induced lung injury (RILI) encompasses any lung toxicity induced by radiation
therapy (RT) and manifests acutely as radiation pneumonitis and chronically as radiation …

Trends in the development of radioprotective agents

SJ Hosseinimehr - Drug discovery today, 2007 - Elsevier
People may be exposed to ionizing radiation during radiotherapy or following exposure to
radionuclides in nuclear medicine. Radioprotective agents have been used to reduce …

A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: management strategies and economic impact

SB Jensen, AML Pedersen, A Vissink… - Supportive care in …, 2010 - Springer
Purpose This systematic review aimed to assess the literature for management strategies
and economic impact of salivary gland hypofunction and xerostomia induced by cancer …

Systematic review of amifostine for the management of oral mucositis in cancer patients

O Nicolatou-Galitis, T Sarri, J Bowen… - Supportive Care in …, 2013 - Springer
Purpose The aim of this study was to review the available literature from 1966 until
December 31, 2010 and define clinical practice guidelines for the use of amifostine for the …

Subcutaneous administration of genistein prior to lethal irradiation supports multilineage, hematopoietic progenitor cell recovery and survival

TA Davis, TK Clarke, SR Mog… - International journal of …, 2007 - Taylor & Francis
Purpose: Genistein, a non-toxic isoflavone from soybeans, has immunomodulating and
radioprotective properties. In this study we investigated the mechanism for genistein …

Subcutaneous compared with intravenous administration of amifostine in patients with head and neck cancer receiving radiotherapy: final results of the GORTEC2000 …

E Bardet, L Martin, G Calais, M Alfonsi… - Journal of clinical …, 2011 - ascopubs.org
Purpose To compare compliance with and efficacy of intravenous (IV) and subcutaneous
(SC) amifostine for the treatment of patients undergoing radiotherapy for head and neck …

Current status of targeted radioprotection and radiation injury mitigation and treatment agents: a critical review of the literature

NS Kalman, SS Zhao, MS Anscher… - International Journal of …, 2017 - Elsevier
As more cancer patients survive their disease, concerns about radiation therapy–induced
side effects have increased. The concept of radioprotection and radiation injury mitigation …

Comparison of effects of dexmedetomidine and amifostine against X-ray radiation-induced parotid damage

G Safak, M Celiker, L Tümkaya, T Mercantepe… - Radiation and …, 2022 - Springer
Radiotherapy can be employed as a therapeutic modality alone in the early stages of cancer
and is used together with other treatments such as surgery and chemotherapy in more …

Alternate delivery route for amifostine as a radio‐/chemo‐protecting agent

NP Praetorius, TK Mandal - Journal of Pharmacy and …, 2008 - Wiley Online Library
Abstract Amifostine (ethiofos, WR‐2721) is an organic thiophosphate prodrug that serves as
an antineoplastic adjunct and cytoprotective agent useful in cancer chemotherapy and …

Modulation of Ionizing Radiation Induced Oxidative Imbalance by Semi‐Fractionated Extract of Piper betle: An In Vitro and In Vivo Assessment

S Verma, ML Gupta, A Dutta… - Oxidative Medicine …, 2010 - Wiley Online Library
The study was planned to evaluate modulatory effect of aqueous extract of Piper betle leaf
(PBL) on ionizing radiation mediated oxidative stress leading to normal tissues damage …