Periodontitis and osteoporosis are prevalent inflammation‐associated skeletal disorders that
pose significant public health challenges to our aging population. Both periodontitis and …

The complement cascade is a critical effector mechanism of the innate immune system that
contributes to the rapid clearance of pathogens and dead or dying cells, as well as …

Acute respiratory distress syndrome (ARDS) is a devastating clinical manifestation of COVID-
19 pneumonia and is mainly based on an immune-driven pathology. Mounting evidence …

Periodontitis is one of the most common dental diseases. Compared with healthy
periodontal tissues, the immune microenvironment plays the key role in periodontitis by …

Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …

Dementia and Alzheimer's disease (AD) are proposed to be comorbid with periodontitis
(PD). It is unclear whether PD is associated with dementia and AD independent of …

Despite the growing recognition of the complement system as a major contributor to a variety
of clinical conditions, the therapeutic arsenal has remained scarce. The introduction of an …

Periodontitis and diabetes are two major global health problems despite their prevalence
being significantly underreported and underestimated. Both epidemiological and …

Objective To identify the relationship between osteoarthritis and periodontitis. Methods
144,788 periodontitis patients and 144,788 propensity score-matched controls without …

Background Periodontitis often causes irrevocable destruction of tooth-supporting tissues
and eventually leads to tooth loss. Currently, stem cell-based tissue engineering has …