Exosomal biomarkers for cancer diagnosis and patient monitoring

A Makler, W Asghar - Expert review of molecular diagnostics, 2020 - Taylor & Francis
Introduction: In recent years, extensive research has been conducted on using exosomes as
biomarkers for cancer detection. Exosomes are 40–150 nm-sized extracellular vesicles …

Jeffery's orbits and microswimmers in flows: A theoretical review

K Ishimoto - Journal of the Physical Society of Japan, 2023 - journals.jps.jp
In this review, we provide a theoretical introduction to Jeffery's equations for the orientation
dynamics of an axisymmetric object in a flow at low Reynolds number, and review recent …

Sperm quality metrics were improved by a biomimetic microfluidic selection platform compared to swim-up methods

SA Vasilescu, L Ding, FY Parast, R Nosrati… - Microsystems & …, 2023 - nature.com
Sperm selection is an essential component of all assisted reproductive treatments (ARTs)
and is by far the most neglected step in the ART workflow in regard to technological …

Surface acoustic wave-driven pumpless flow for sperm rheotaxis analysis

J Gai, C Devendran, A Neild, R Nosrati - Lab on a Chip, 2022 - pubs.rsc.org
Sperm rheotaxis, the phenomenon where sperm cells swim against the direction of fluid
flow, is one of the major guiding mechanisms for long-distance sperm migration within the …

IVF-on-a-chip: recent advances in microfluidics technology for in vitro fertilization

L Weng - SLAS TECHNOLOGY: Translating Life Sciences …, 2019 - journals.sagepub.com
In vitro fertilization (IVF) has been one of the most exciting modern medical technologies. It
has transformed the landscape of human infertility treatment. However, current IVF …

Development of a flow-free magnetic actuation platform for an automated microfluidic ELISA

C Coarsey, B Coleman, MA Kabir, M Sher, W Asghar - RSC advances, 2019 - pubs.rsc.org
There is a need to create an easily deployable and point-of-care (POC) diagnostic platform
for disease outbreaks and for monitoring and maintenance of chronic illnesses. Such …

Lab-on-a-chip zika detection with reverse transcription Loop-mediated isothermal amplification–based assay for point-of-care settings

S Sharma, MA Kabir, W Asghar - Archives of pathology & …, 2020 - meridian.allenpress.com
Context.—Zika virus (ZIKV) infection, primarily transmitted by mosquitoes, causes various
neurologic disorders. To differentiate ZIKV from other arboviruses, such as dengue …

Pump-Free Microfluidic Device for the Electrochemical Detection of α1-Acid Glycoprotein

T Sierra, I Jang, E Noviana, AG Crevillen… - ACS …, 2021 - ACS Publications
α1-Acid glycoprotein (AGP) is a glycoprotein present in serum, which is associated with the
modulation of the immune system in response to stress or injuries, and a biomarker for …

Smartphone-based sickle cell disease detection and monitoring for point-of-care settings

S Ilyas, M Sher, E Du, W Asghar - Biosensors and Bioelectronics, 2020 - Elsevier
Sickle cell disease (SCD) is a worldwide hematological disorder causing painful episodes,
anemia, organ damage, stroke, and even deaths. It is more common in sub-Saharan Africa …

Microfluidics: The future of sperm selection in assisted reproduction

AR Jahangiri, N Ziarati, E Dadkhah, MN Bucak… - …, 2024 - Wiley Online Library
Background Obtaining functional sperm cells is the first step to treat infertility. With the ever‐
increasing trend in male infertility, clinicians require access to effective solutions that are …