Could eggshell membrane be an adjuvant for recombinant Hepatitis B vaccine?: A preliminary investigation

PE Joshua, CC Ilo, UG Ukachukwu… - Future Journal of …, 2023 - Springer
Background Despite the invasiveness of the Hepatitis B infection, its vaccines are only
formulated with FDA-approved alum-based adjuvants, which poorly elicit a lasting immune …

Formulation of HBsAg in Montanide ISA 51VG adjuvant: Immunogenicity study and monitoring long-lived humoral immune responses

MA Savoji, MMA Sereshgi, SMM Ghahari… - International …, 2021 - Elsevier
Montanide ISA 51VG adjuvant has been approved for human clinical application and
stimulates cellular and humoral immune responses. Here, HBsAg was formulated in …

Formulation of a recombinant HIV‐1 polytope candidate vaccine with naloxone/alum mixture: Induction of multi‐cytokine responses with a higher regulatory …

M Fathi, R Nezamzadeh, M Abdollahpour‐Alitappeh… - Apmis, 2021 - Wiley Online Library
The potency of a vaccine highly depends upon the nature of the adjuvant used. There are a
variety of ineffective vaccines, such as HIV‐1 vaccine candidates, that need to be optimized …

Montanide ISA-720 and Naloxone in HBsAg Vaccine Formulation: Cytokine Profiling and Monitoring of Long-Lasting Humoral Immune Responses

M Mirzaee, S Haghighat, B Golkaran… - Biomedical and …, 2022 - Elsevier
Objective This study aimed to investigate the effects of Montanide ISA-720 and Naloxone
(NLX) in Hepatitis B surface antigen (HBsAg) vaccine formulation on cytokine and long …

Experimental and molecular predictions of the adjuvanticity of snail mucin on hepatitis B vaccine in albino mice

PE Joshua, CO Nwauzor, DC Odimegwu… - PLoS …, 2021 - journals.plos.org
Although aluminum-containing adjuvants are widely used in human vaccination due to their
excellent safety profile, they exhibit low effectiveness with many recombinant antigens. This …

Improvement of hepatitis B vaccine to induce IFN-γ cytokine response: A new formulation

A Rahimkhani, S Haghighat, H Noorbazargan… - Microbial …, 2021 - Elsevier
Hepatitis B virus (HBV) infection is limited through vaccination against HBsAg formulated in
the Alum adjuvant. However, this alum-formulated vaccine fails to be preventive in some …

[HTML][HTML] Fast antibody responses by immuno-targeting and nanotechnology strategies versus HBsAg vaccine

M Rezaei, SN Hosseini, RA Khavari-Nejad… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): Though immunization with HBsAg has been routine since the 1980s, it has
numerous limitations such as low or none humoral immune responses. Today …

Experimental and immunoinformatic studies revealed an enhanced immune responses of recombinant hepatitis B vaccine on eggshell membrane adjuvant

PE Joshua, C Ilo, U Ukachukwu… - Available at SSRN …, 2021 - papers.ssrn.com
Despite the invasiveness of the Hepatitis-B infection, its vaccines are only formulated with
FDA-approved alum-based adjuvants, which poorly elicit a lasting immune response. Hence …

[引用][C] Chitin As A Possible Adjuvant For Recombinant Hepatitis B Vaccine In Mice

NE Ayogu - 2018 - University of Nigeria, Nsukka