Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

The strategies involved in the development of therapeutics for neurodegenerative disorders
are very complex and challenging due to the existence of the blood-brain barrier (BBB), a …

Neutrophils are the most abundant innate immune cells in human circulation; however, their
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …

Theranostic sonosensitizers with combined sonodynamic and near infrared (NIR) imaging
modes are required for imaging guided sonodynamic therapy (SDT). It is challenging …

Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …

Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …

Abstract Background MiR-199a-3p (miR-199a) can enhance the chemosensitivity of
hepatocellular carcinoma (HCC). Because of the easy degradation of miRNA by direct …

Biofuel cells (BFCs)-based self-powered biosensors suffer from the limited stability of
bioenzymes. Meanwhile, the poor performance of self-powered biosensors affects the …

The recently described role of RNA methylation in regulating immune cell infiltration into
tumors has attracted interest, given its potential impact on immunotherapy response …