Modulatory effect of lifestyle-related, environmental and genetic factors on paraoxonase-1 activity: a review

D Kunachowicz, M Ściskalska, M Kepinska - International Journal of …, 2023 - mdpi.com
Paraoxonase-1 (PON1) is a calcium-dependent, HDL-bound serum hydrolase active toward
a wide variety of substrates. PON1 displays three types of activities, among which lactonase …

Paraoxonase-1: How a xenobiotic detoxifying enzyme has become an actor in the pathophysiology of infectious diseases and cancer

J Camps, S Iftimie, M Arenas, H Castañé… - Chemico-Biological …, 2023 - Elsevier
Both infectious and non-infectious diseases can share common molecular mechanisms,
including oxidative stress and inflammation. External factors, such as bacterial or viral …

Protective Effect of Limosilactobacillus fermentum ME-3 against the Increase in Paracellular Permeability Induced by Chemotherapy or Inflammatory Conditions in …

A De Gregorio, A Serafino, EK Krasnowska… - International Journal of …, 2023 - mdpi.com
Chemotherapy-or inflammation-induced increase in intestinal permeability represents a
severe element in disease evolution in patients suffering from colorectal cancer and gut …

Correlation of endoplasmic reticulum stress patterns with the immune microenvironment in hepatocellular carcinoma: a prognostic signature analysis

K Zhan, X Yang, S Li, Y Bai - Frontiers in Immunology, 2023 - frontiersin.org
Backgrounds The extended duration of endoplasmic reticulum stress (ERS) can impact the
progression of hepatocellular carcinoma (HCC) and the efficacy of immunotherapies by …

Analysis of redox status and HDL subclasses in patients with lymphoma and the associations with FDG-PET/CT findings

B Mirjanic-Azaric, S Stankovic, L Nezic… - Frontiers in …, 2023 - frontiersin.org
Newer research points to alterations in the plasma redox status and the HDL subclass
distributions in cancer. We aimed to assess the redox status and the HDL subclass …

Importance of Polymorphisms in the Gene of Paraoxonase-1 (SNP rs662) and Apolipoprotein AI (SNP rs670 and rs5069) in Non-Smoking and Smoking Healthy …

M Ściskalska, H Milnerowicz - Genes, 2022 - mdpi.com
Oxidative stress has been implicated in the initiation of acute pancreatitis (AP). HDL is
considered to be a preventing factor against cell membrane oxidation, thanks to the …

Evaluation of paraoxonase-1 and pentraxin-3 in the diagnosis and prognosis of endometrial cancer

M Kozłowski, K Michalczyk, G Witczak, S Kwiatkowski… - Antioxidants, 2022 - mdpi.com
It is relevant to find new prognostic and diagnostic biomarkers for endometrial cancer. The
study group consisted of 94 cases of endometrial cancer, the control group of 65 cases of …

Effects of thymoquinone and the curcumin analog EF-24 on the activity of the enzyme paraoxonase-1 in human glioblastoma cells U87MG

E Simsek, A Sunguroglu, A Kilic… - Journal of Enzyme …, 2024 - Taylor & Francis
The spices and aromatic herbs were used not only in cooking to add flavour and smell to
dishes but also for medicinal use. Nigella sativa, also called black cumin, is one of the …

[HTML][HTML] Oxidative Status and Lipid Metabolism Analytes in Dogs with Mast Cell Tumors: A Preliminary Study

A Ginoudis, D Pardali, ME Mylonakis… - …, 2024 - pmc.ncbi.nlm.nih.gov
Mast cell tumors (MCTs) are common skin neoplasms in dogs. Prognostic indicators include
histologic grade, clinical stage, high Ki-67 index, elevated argyrophilic nucleolus organizer …

The increased antioxidant action of HDL is independent of HDL cholesterol plasma levels in triple-negative breast cancer

AL Campos, MIBAC Sawada, MFM Santana… - Frontiers in …, 2023 - frontiersin.org
Introduction The association between high-density lipoprotein cholesterol (HDLc) with the
incidence and progression of breast cancer (BC) is controversial. HDL removes excess …