Recent research using Drosophila melanogaster has seen a resurgence in studies of metabolism and physiology. This review focuses on major methods used to conduct this …
WB Dunn, D Broadhurst, P Begley, E Zelena… - Nature protocols, 2011 - nature.com
Metabolism has an essential role in biological systems. Identification and quantitation of the compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
JF Xiao, B Zhou, HW Ressom - TrAC Trends in Analytical Chemistry, 2012 - Elsevier
Metabolomics aims at detection and quantitation of all metabolites in biological samples. The presence of metabolites with a wide variety of physicochemical properties and different …
DQ Tang, L Zou, XX Yin, CN Ong - Mass spectrometry reviews, 2016 - Wiley Online Library
Hydrophilic interaction chromatography (HILIC) is an emerging separation mode of liquid chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …
Life history theory seeks to explain the evolution of the major features of life cycles by analyzing the ecological factors that shape age-specific schedules of growth, reproduction …
This review focuses on recent advances in instrumentation, techniques, and applications of the highest resolution mass analyzers (multipass time of flight (TOF), orbitrap, and Fourier …
To build a credible model for given chemical or biological or clinical data, it may be helpful to first get somewhat better insight into the data itself before modeling and then to present the …
A Makarov, M Scigelova - Journal of Chromatography A, 2010 - Elsevier
The Orbitrap mass analyzer has become a mainstream mass spectrometry technique. In addition to providing a brief introduction to the Orbitrap technology and its continuing …
The chemical identification of mass spectrometric signals in metabolomic applications is important to provide conversion of analytical data to biological knowledge about metabolic …