Scorpions are well known for their dangerous stings that can result in severe consequences
for human beings, including death. Neurotoxins present in their venoms are responsible for …

The potential use of antisense and siRNA oligonucleotides as therapeutic agents has
elicited a great deal of interest. However, a major issue for oligonucleotide-based …

Both purinergic signaling through nucleotides such as ATP (adenosine 5′-triphosphate)
and noradrenergic signaling through molecules such as norepinephrine regulate vascular …

Considering the problems of small interfering RNA (siRNA) delivery using traditional viral
and nonviral vehicles, a new siRNA delivery system to enhance efficiency and safety needs …

There has been great progress in the use of TAT-based drug delivery systems for the
delivery of different macromolecules into cells in vitro and in vivo, thus circumventing the …

Results and perspectives on the biomedical exploitation of gold nanorods with plasmon
resonances in the near infrared window are reported. The authors describe experimental …

Gene therapy is the ultimate therapeutic technology for diseases related to gene
abnormality. However, the use of DNA alone has serious problems, such as poor stability …

Purpose The aim of this study is to overcome tumour cell resistance that generally develops
after administration of commonly used anti-cancer drugs, such as doxorubicin. Methods …

Cell penetrating peptides (CPPs) have been extensively studied in polyelectrolyte
complexes as a means to enhance the transfection efficiency of plasmid DNA (pDNA) …

The replication of many retroviruses is mediated by a transcriptional activator protein, Tat,
which activates RNA polymerase II at the level of transcription elongation. Tat interacts with …