Breast cancer genome-wide association studies: there is strength in numbers
D Fanale, V Amodeo, LR Corsini, S Rizzo, V Bazan… - Oncogene, 2012 - nature.com
Breast cancer (BC) is a heterogeneous disease that exhibits familial aggregation. Family
linkage studies have identified high-penetrance genes, BRCA1, BRCA2, PTEN and TP53 …
linkage studies have identified high-penetrance genes, BRCA1, BRCA2, PTEN and TP53 …
Common breast cancer risk variants in the post-COGS era: a comprehensive review
KN Maxwell, KL Nathanson - Breast Cancer Research, 2013 - Springer
Breast cancer has a strong heritable component, with approximately 15% of cases exhibiting
a family history of the disease. Mutations in genes such as BRCA1, BRCA2 and TP53 lead …
a family history of the disease. Mutations in genes such as BRCA1, BRCA2 and TP53 lead …
Genetic modifiers of CHEK2* 1100delC-associated breast cancer risk
TA Muranen, D Greco, C Blomqvist, K Aittomäki… - Genetics in …, 2017 - nature.com
Purpose: CHEK2* 1100delC is a founder variant in European populations that confers a two-
to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have …
to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have …
Association of FGFR2 rs2981582 polymorphism and breast cancer susceptibility: An updated systematic review and meta-analysis
SK Yasam, G Chandrashekar, P Ganapathy… - Human Gene, 2023 - Elsevier
The present meta-analysis aims to determine whether Fibroblast Growth Factor Receptor
2.(FGFR2) FGFR2 rs2981582 gene polymorphisms are associated with a mammary …
2.(FGFR2) FGFR2 rs2981582 gene polymorphisms are associated with a mammary …
Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes
M Riaz, EMJJ Berns, AM Sieuwerts… - Breast cancer research …, 2012 - Springer
To understand the biology of low-risk breast cancer alleles, and to investigate whether these
loci also contribute to disease progression that was once established, we examined the …
loci also contribute to disease progression that was once established, we examined the …
Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development
Background Human chromosomal region 8q24 contains several genes which could be
functionally related to cancer, including the proto-oncogene c-MYC. However, the …
functionally related to cancer, including the proto-oncogene c-MYC. However, the …
Variants of FGFR2 and their associations with breast cancer risk: a HUGE systematic review and meta-analysis
F Cui, D Wu, W Wang, X He, M Wang - Breast cancer research and …, 2016 - Springer
Extensive epidemiological studies have demonstrated that there are associations between
variants in intron 2 of FGFR2 and the breast cancer risk in various populations; however, the …
variants in intron 2 of FGFR2 and the breast cancer risk in various populations; however, the …
Frequent mutation of rs13281615 and its association with PVT1 expression and cell proliferation in breast cancer
The q24 band of chromosome 8 (8q24) is frequently amplified in human cancers including
breast cancer, and several SNPs (single nucleotide polymorphisms) at 8q24, including …
breast cancer, and several SNPs (single nucleotide polymorphisms) at 8q24, including …
Distribution of FGFR2, TNRC9, MAP3K1, LSP1, and 8q24 alleles in genetically enriched breast cancer patients versus elderly tumor-free women
TV Gorodnova, ES Kuligina… - Cancer genetics …, 2010 - cancergeneticsjournal.org
Recent genome-wide association studies (GWAS) have led to the identification of several
breast cancer (BC) epredisposing single nucleotide polymorphisms (SNPs)[1e8]. To our …
breast cancer (BC) epredisposing single nucleotide polymorphisms (SNPs)[1e8]. To our …
Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) …
Introduction Genome-wide association studies, focusing primarily on unilateral breast
cancer, have identified single nucleotide polymorphisms (SNPs) in a number of genomic …
cancer, have identified single nucleotide polymorphisms (SNPs) in a number of genomic …