Worldwide control and management of Chagas disease in a new era of globalization: a close look at congenital Trypanosoma cruzi infection

A Abras, C Ballart, A Fernández-Arévalo… - Clinical microbiology …, 2022 - Am Soc Microbiol
Population movements have turned Chagas disease (CD) into a global public health
problem. Despite the successful implementation of subregional initiatives to control vectorial …

Retrospect, advances and challenges in Chagas disease diagnosis: A comprehensive review

AG Schijman, J Alonso-Padilla, C Britto… - The Lancet Regional …, 2024 - thelancet.com
Chagas disease, caused by Trypanosoma cruzi, affects millions worldwide. The 2030 WHO
roadmap aims to eliminate it as a public health concern, emphasising the need for timely …

Comparison of the Influence of Different Nucleic Acid Extraction Assays on the Sensitivity of Trypanosoma cruzi-Specific Real-Time PCR

S Kann, W Zabala-Monterroza, C García, G Concha… - Microorganisms, 2022 - mdpi.com
For the molecular diagnosis of Chagas disease by real-time PCR (polymerase chain
reaction), optimization of diagnostic accuracy is desirable. The detection limit of real-time …

A Questionnaire Integrated with the Digital Medical Record Improved the Coverage of a Control Program for Congenital Chagas Disease in Tuscany, Italy

A Barbiero, M Mazzi, A Mantella, M Trotta… - Microorganisms, 2023 - mdpi.com
The leading route of Chagas disease transmission in nonendemic countries is congenital.
However, policies concerning screening, prevention, and management of congenital …

Validation of the NAT Chagas IVD Kit for the Detection and Quantification of Trypanosoma cruzi in Blood Samples of Patients with Chagas Disease

OC Moreira, AG Fernandes, NLS Gomes… - Life, 2023 - mdpi.com
In the absence of validated biomarkers to control the cure of Chagas disease, PCR-based
diagnosis is being used as the main tool for an early indication of therapeutic failure …

Comparative Assessment of Two Commercial Real-Time PCR Assays for the Diagnosis of Trypanosoma cruzi DNA in Serum

S Kann, G Concha, F Weinreich, A Hahn, C Rückert… - Microorganisms, 2023 - mdpi.com
This study was performed to comparably assess two commercial real-time PCR assays for
the identification of Trypanosoma cruzi DNA in serum. A total of 518 Colombian serum …

Parasitemia levels in Trypanosoma cruzi infection in Spain, an area where the disease is not endemic: trends by different molecular approaches

MD Flores-Chavez, A Abras, C Ballart… - Microbiology …, 2022 - Am Soc Microbiol
Trypanosoma cruzi infection has expanded globally through human migration. In Spain, the
mother-to-child route is the mode of transmission contributing to autochthonous Chagas …

Molecular Detection of Neglected Tropical Diseases: The Case for Automated Near–Point-of-Care Diagnosis of Leishmaniasis

I Gow, N Smith, D Stark, J Ellis - The American Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Neglected tropical diseases affect those in poorer nations disproportionately across the
globe. One example of these, leishmaniasis, is a debilitating and potentially fatal parasitic …

Retrospect, advances and challenges in Chagas disease diagnosis: a comprehensive review

A Gabriel Schijman, J Alonso-Padilla, CFDPC Britto… - 2024 - arca.fiocruz.br
Chagas disease, caused by Trypanosoma cruzi, affects millions worldwide. The 2030 WHO
roadmap aims to eliminate it as a public health concern, emphasising the need for timely …

Worldwide Control and Management of Chagas Disease in a New Era of Globalization: a Close Look at Congenital Trypanosoma cruzi Infection

A Abras Feliu, C Ballart… - … Reviews, 2022, vol …, 2022 - dugi-doc.udg.edu
Population movements have turned Chagas disease (CD) into a global public health
problem. Despite the successful implementation of subregional initiatives to control vectorial …