Ethnopharmacological relevance Cerebral ischemia/reperfusion (I/R) injury is a major cause
of neuronal damage and death. Ginkgolide B (GB) has been shown to exhibit …

Oleuropein plays a key role as a pro-oxidant as well as an antioxidant in cancer. In this
study, the activity of oleuropein, in an in vitro model of ovarian (OCCs) and breast cancer …

Oral squamous cell carcinoma (OSCC) is an aggressive disease and one of the most
prevalent head and neck malignancy (1). The pathogenesis of OSCC is a multistep process …

Emerging evidence shows that oral squamous cell carcinoma (OSCC) invasiveness can be
attributed to a small subpopulation of cancer stem cells (CSCs) in the bulk of the tumor …

Oxidative stress is the major culprits responsible for ovarian dysfunction by damaging
granulosa cells (GCs). Ferritin heavy chain (FHC) may participate in the regulation of …

Purpose Iron acquisition is key to maintaining cell survival and function. Cancer cells in
general are considered to have an insatiable iron need. Iron delivery via the …

Introduction: The PD-1/PD-L1 axis is hijacked by lung adenocarcinoma (LUAD) cells to
escape immune surveillance. PD-L1 expression in LUAD is affected, among others, by the …

Abstract The SARS-CoV-2 pandemic, responsible for approximately 7 million deaths
worldwide, highlights the urgent need to understand the molecular mechanisms of the virus …

T cells are among the most potent anti-tumor cells that are found in humans. Our study
sought to develop a reliable signature incorporating T cell marker genes (TMGs) for …

Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine protein kinase involved in
human brain development and functioning. Mutations in CDKL5, especially in its catalytic …