Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been
proposed to be a therapeutic target for reducing the impact of emotional memories that can …

Addiction is a chronic, relapsing disorder. The progression to pathological drug-seeking is
thought to be driven by maladaptive learning processes which store and maintain …

Risk of relapse is a major challenge in the treatment of substance use disorders. Several
types of learning and memory mechanisms are involved in substance use and have …

Substance abuse is one of the significant problems in social and public health worldwide.
Vast numbers of evidence illustrate that motivational and reinforcing impacts of addictive …

The basolateral amygdala (BLA) is a critical brain region for cocaine-memory
reconsolidation. Corticotropin-releasing factor receptor type 1 (CRFR1) is densely …

Persistent and intrusive memories define a number of psychiatric disorders, including
posttraumatic stress disorder and substance use disorder. In the latter, memory for drug …

Re-exposure to a cocaine-associated context triggers craving and relapse through the
retrieval of salient context-drug memories. Upon retrieval, context-drug memories become …

Contextual drug-associated memories precipitate craving and relapse in cocaine users.
Such associative memories can be weakened through interference with memory …

The infralimbic (IL) cortex of the medial prefrontal cortex plays an important role in the
extinction of fear memory. Also, it has been showed that both brain glucocorticoid and …

The biological stress response of the body forms one of the foundations of adaptive
behavior, including promoting (and impairing) different forms of memory. This response …