Long-range mechanical signaling in biological systems
Cells can respond to signals generated by other cells that are remarkably far away. Studies
from at least the 1920's showed that cells move toward each other when the distance …
from at least the 1920's showed that cells move toward each other when the distance …
Multi-scale modeling of the cardiovascular system: disease development, progression, and clinical intervention
Cardiovascular diseases (CVDs) are the leading cause of death in the western world. With
the current development of clinical diagnostics to more accurately measure the extent and …
the current development of clinical diagnostics to more accurately measure the extent and …
Cell contact guidance via sensing anisotropy of network mechanical resistance
Despite the ubiquitous importance of cell contact guidance, the signal-inducing contact
guidance of mammalian cells in an aligned fibril network has defied elucidation. This is due …
guidance of mammalian cells in an aligned fibril network has defied elucidation. This is due …
Normal and fibrotic rat livers demonstrate shear strain softening and compression stiffening: a model for soft tissue mechanics
Tissues including liver stiffen and acquire more extracellular matrix with fibrosis. The
relationship between matrix content and stiffness, however, is non-linear, and stiffness is …
relationship between matrix content and stiffness, however, is non-linear, and stiffness is …
Light-sheet photonic force optical coherence elastography for high-throughput quantitative 3D micromechanical imaging
Quantitative characterisation of micro-scale mechanical properties of the extracellular matrix
(ECM) and dynamic cell-ECM interactions can significantly enhance fundamental …
(ECM) and dynamic cell-ECM interactions can significantly enhance fundamental …
Increasing Cell Seeding Density Improves Elastin Expression and Mechanical Properties in Collagen Gel‐Based Scaffolds Cellularized with Smooth Muscle Cells
Vascular tissue engineering combines cells with scaffold materials in vitro aiming the
development of physiologically relevant vascular models. For natural scaffolds such as …
development of physiologically relevant vascular models. For natural scaffolds such as …
Multiscale mechanical model of the Pacinian corpuscle shows depth and anisotropy contribute to the receptor's characteristic response to indentation
JC Quindlen, VK Lai, VH Barocas - PLoS computational biology, 2015 - journals.plos.org
Cutaneous mechanoreceptors transduce different tactile stimuli into neural signals that
produce distinct sensations of touch. The Pacinian corpuscle (PC), a cutaneous …
produce distinct sensations of touch. The Pacinian corpuscle (PC), a cutaneous …
Cellular microbiaxial stretching to measure a single-cell strain energy density function
Z Win, JM Buksa, KE Steucke… - Journal of …, 2017 - asmedigitalcollection.asme.org
The stress in a cell due to extracellular mechanical stimulus is determined by its mechanical
properties, and the structural organization of many adherent cells suggests that their …
properties, and the structural organization of many adherent cells suggests that their …
Galactose enhances chondrogenic differentiation of ATDC5 and cartilage matrix formation by chondrocytes
Z Yuan, S Liu, W Song, Y Liu, G Bi, R Xie… - Frontiers in Molecular …, 2022 - frontiersin.org
Galactose, an important carbohydrate nutrient, is involved in several types of cellular
metabolism, participating in physiological activities such as glycosaminoglycan (GAG) …
metabolism, participating in physiological activities such as glycosaminoglycan (GAG) …
Multiscale modeling of growth plate cartilage mechanobiology
J Gao, JL Williams, E Roan - Biomechanics and modeling in …, 2017 - Springer
Growth plate chondrocytes are responsible for bone growth through proliferation and
differentiation. However, the way they experience physiological loads and regulate bone …
differentiation. However, the way they experience physiological loads and regulate bone …