Mitochondrial membrane lipids in the regulation of bioenergetic flux

ST Decker, K Funai - Cell metabolism, 2024 - cell.com
Oxidative phosphorylation (OXPHOS) occurs through and across the inner mitochondrial
membrane (IMM). Mitochondrial membranes contain a distinct lipid composition, aided by …

START ships lipids across interorganelle space

F Alpy, C Tomasetto - Biochimie, 2014 - Elsevier
The family of StAR related lipid transfer proteins (START) is so-named based on the
distinctive capacity for these proteins to transport lipids between membranes. The START …

Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3

RT Florian, F Kraft, E Leitão, S Kaya, S Klebe… - Nature …, 2019 - nature.com
Abstract Familial Adult Myoclonic Epilepsy (FAME) is a genetically heterogeneous disorder
characterized by cortical tremor and seizures. Intronic TTTTA/TTTCA repeat expansions in …

Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis

N Rosewick, K Durkin, M Artesi, A Marcais… - Nature …, 2017 - nature.com
Human T-cell leukaemia virus type-1 (HTLV-1) and bovine leukaemia virus (BLV) infect T-
and B-lymphocytes, respectively, provoking a polyclonal expansion that will evolve into an …

Intronic ATTTC repeat expansions in STARD7 in familial adult myoclonic epilepsy linked to chromosome 2

MA Corbett, T Kroes, L Veneziano, MF Bennett… - Nature …, 2019 - nature.com
Abstract Familial Adult Myoclonic Epilepsy (FAME) is characterised by cortical myoclonic
tremor usually from the second decade of life and overt myoclonic or generalised tonic …

The START-domain proteins in intracellular lipid transport and beyond

BJ Clark - Molecular and cellular endocrinology, 2020 - Elsevier
Abstract The Steroidogenic Acute R egulatory Protein-related Lipid T ransfer (START)
domain is a~ 210 amino acid sequence that folds into an α/β helix-grip structure forming a …

The phosphatidylcholine transfer protein Stard7 is required for mitochondrial and epithelial cell homeostasis

L Yang, CL Na, S Luo, D Wu, S Hogan, T Huang… - Scientific reports, 2017 - nature.com
Mitochondria synthesize select phospholipids but lack the machinery for synthesis of the
most abundant mitochondrial phospholipid, phosphatidylcholine (PC). Although the …

Differential regulatory roles of MicroRNAs in porcine intramuscular and subcutaneous adipocytes

K Xu, M Ji, X Huang, Y Peng, W Wu… - Journal of agricultural …, 2020 - ACS Publications
The deposition of intramuscular (IM) and subcutaneous (SC) fat is an important trait
influencing pork quality. Understanding the genetic differences between these two types of …

Steroidogenic acute regulatory protein: structure, functioning, and regulation

KV Tugaeva, NN Sluchanko - Biochemistry (Moscow), 2019 - Springer
Steroidogenesis takes place mainly in adrenal and gonadal cells that produce a variety of
structurally similar hormones regulating numerous body functions. The rate-limiting stage of …

STARD3: a prospective target for cancer therapy

K Asif, L Memeo, S Palazzolo, Y Frión-Herrera, S Parisi… - Cancers, 2021 - mdpi.com
Simple Summary Alterations in cholesterol level play an important role in cancer
development. Lipid transfer proteins (LTPs) are involved in cholesterol distribution between …