American Association of Oral and Maxillofacial Surgeons' position paper on medication-related osteonecrosis of the jaws—2022 update

SL Ruggiero, TB Dodson, T Aghaloo… - Journal of oral and …, 2022 - Elsevier
Strategies for management of patients with, or at risk for, medication-related osteonecrosis of
the jaws (MRONJ)–formerly referred to as bisphosphonate-related osteonecrosis of the jaws …

Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)

JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

Mitigating osteonecrosis of the jaw (ONJ) through preventive dental care and understanding of risk factors

JT Wan, DM Sheeley, MJ Somerman, JS Lee - Bone research, 2020 - nature.com
It is well established that alterations in phosphate metabolism have a profound effect on
hard and soft tissues of the oral cavity. The present-day clinical form of osteonecrosis of the …

Biologic and pathologic aspects of osteocytes in the setting of medication-related osteonecrosis of the jaw (MRONJ)

JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe, debilitating
condition affecting patients with cancer and patients with osteoporosis who have been …

Pathophysiology of Medication‐Related Osteonecrosis of the Jaw—A Minireview

S Tetradis, MR Allen, SL Ruggiero - Journal of Bone and Mineral …, 2023 - academic.oup.com
Medication‐related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse effect of
antiresorptive medications administered for control of osseous malignancy, osteoporosis, or …

Establishment and assessment of rodent models of medication-related osteonecrosis of the jaw (MRONJ)

R Yan, R Jiang, L Hu, Y Deng, J Wen… - International journal of …, 2022 - nature.com
Medication-related osteonecrosis of the jaw (MRONJ) is primarily associated with
administering antiresorptive or antiangiogenic drugs. Despite significant research on …

Preventing or controlling periodontitis reduces the occurrence of osteonecrosis of the jaw (ONJ) in rice rats (Oryzomys palustris)

EJ Castillo, JG Messer, AM Abraham, JM Jiron… - Bone, 2021 - Elsevier
Introduction Osteonecrosis of the jaw (ONJ) is an adverse event that requires association of
both systemic risk factors, such as powerful anti-resorptives (pARs; eg zoledronic acid …

Effects of anti-resorptive drugs on implant survival and peri-implantitis in patients with existing osseointegrated dental implants: a retrospective cohort study

JY Kim, H Choi, JH Park, HD Jung, YS Jung - Osteoporosis International, 2020 - Springer
The effect of anti-resorptive drug (ARD) usage among patients with successful dental
implant osseointegration is controversial. This study showed an increased risk of implant …

Anti-vascular endothelial growth factor antibody monotherapy causes destructive advanced periodontitis in rice rats (Oryzomys palustris)

JG Messer, EJ Castillo, AM Abraham, JM Jiron, R Israel… - Bone, 2020 - Elsevier
Abstract Objective Angiogenesis inhibitors (AgI) are commonly used in combination
chemotherapy protocols to treat cancer, and have been linked to osteonecrosis of the jaw …

Management of medication‐related osteonecrosis of jaw: Comparison between icariin and teriparatide in a rat model

J Liu, N Mattheos, C Deng, C Su, Z Wang… - Journal of …, 2021 - Wiley Online Library
Background The aim of this study is to compare the effects of icariin and teriparatide on the
treatment of medication‐related osteonecrosis of the jaw (MRONJ) using a rat model …