Obesity is caused by a long-term difference between energy intake and expenditure—an
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …

The gut microbiota is a central regulator of host metabolism. The composition and function of
the gut microbiota is dynamic and affected by diet properties such as the amount and …

Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

Bacteria from the Turicibacter genus are prominent members of the mammalian gut
microbiota and correlate with alterations in dietary fat and body weight, but the specific …

Diet affects multiple facets of human health and is inextricably linked to chronic metabolic
conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients …

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …

Lipids entering the gastrointestinal tract include dietary lipids (triacylglycerols, cholesteryl
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …

Background & Aims Fatty liver disease, including non-alcoholic fatty liver (NAFLD) and
steatohepatitis (NASH), has been associated with increased intestinal barrier permeability …

Obesity is a global epidemic characterized by energy disequilibrium, metabolic disorder, fat
mass development, and chronic low-grade inflammation, which significantly affects the …

The intestinal microbiota regulates mammalian lipid absorption, metabolism, and storage.
We report that the microbiota reprograms intestinal lipid metabolism in mice by repressing …