Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …

Mitochondrial dysfunction has been implicated in the development of heart failure. Oxidative
metabolism in mitochondria is the main energy source of the heart, and the inability to …

Major reactive oxygen species (ROS)–producing systems in vascular wall include NADPH
(reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase …

This review examines the generation of reactive oxygen species by mammalian
mitochondria, and the status of different sites of production in redox signaling and pathology …

Background Inflammation, oxidative stress, and apoptosis contribute to the evolution of
doxorubicin (DOX)‐induced cardiotoxicity. Osteocrin (OSTN) is a novel secretory peptide …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from
aerobic metabolism, as a result of accidental electron leakage as well as regulated …

Mitochondria serves a primary role in energy maintenance but also function to govern levels
of mitochondria-derived reactive oxygen species (mROS). ROS have long been established …

Canonical functions of mitochondria include the regulation of cellular survival, orchestration
of anabolic and metabolic pathways, as well as reactive oxygen species (ROS) signaling …

The heart is capable of responding to stressful situations by increasing muscle mass, which
is broadly defined as cardiac hypertrophy. This phenomenon minimizes ventricular wall …

White adipose tissues (WAT) play crucial roles in maintaining whole-body energy
homeostasis, and their dysfunction can contribute to hepatic insulin resistance and type 2 …