Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS

L Liu, JR Huh, K Shah - EBioMedicine, 2022 - thelancet.com
The recent revelation that the gut microbiome, home to approximately 100 trillion
microorganisms, is implicated in the development of both health and disease has spurred an …

Therapeutic targeting of glioblastoma and the interactions with its microenvironment

V Genoud, B Kinnersley, NF Brown, D Ottaviani… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most aggressive brain tumour. Patients with
GBM have a dismal survival and there is a distinct lack of curative treatments. We are …

Butyrate ameliorates colorectal cancer through regulating intestinal microecological disorders

J Kang, M Sun, Y Chang, H Chen, J Zhang… - Anti-Cancer …, 2023 - journals.lww.com
The occurrence and progression of colorectal cancer (CRC) are closely related to intestinal
microecological disorders. Butyrate, the representative of short chain fatty acids, possess …

Bifidobacterium lactis combined with Lactobacillus plantarum inhibit glioma growth in mice through modulating PI3K/AKT pathway and gut microbiota

L Wang, S Li, H Fan, M Han, J Xie, J Du… - Frontiers in …, 2022 - frontiersin.org
Glioma is a common primary aggressive tumor with limited clinical treatment. Recently,
growing research suggests that gut microbiota is involved in tumor progression, and several …

The role of gut microbiota in patients with benign and malignant brain tumors: a pilot study

H Jiang, W Zeng, X Zhang, Y Pei, H Zhang, Y Li - Bioengineered, 2022 - Taylor & Francis
Gut microbiota is associated with the growth of various tumors, including malignant gliomas,
through the brain-gut axis. Moreover, the gut microbiota in patients with malignant tumors …

Gliomas: Genetic alterations, mechanisms of metastasis, recurrence, drug resistance, and recent trends in molecular therapeutic options

S Kannan, AK Murugan, S Balasubramanian… - Biochemical …, 2022 - Elsevier
Glioma is the most common intracranial tumor with poor treatment outcomes and has high
morbidity and mortality. Various studies on genomic analyses of glioma found a variety of …

Gut microbiome alterations affect glioma development and Foxp3 expression in tumor microenvironment in mice

Y Fan, Q Su, J Chen, Y Wang, S He - Frontiers in Oncology, 2022 - frontiersin.org
Glioma is the most common malignant tumor of the central nervous system (CNS), with high
degree of malignancy and poor prognosis. The gut microbiome (GM) is composed of …

Gut microbiota mediated the individualized efficacy of Temozolomide via immunomodulation in glioma

X Hou, H Du, Y Deng, H Wang, J Liu, J Qiao… - Journal of Translational …, 2023 - Springer
Background Temozolomide (TMZ) is the preferred chemotherapy strategy for glioma
therapy. As a second-generation alkylating agent, TMZ provides superior oral bio …

Predictive microbial feature analysis in patients with depression after acute ischemic stroke

S Yao, H Xie, Y Wang, N Shen, Q Chen… - Frontiers in Aging …, 2023 - frontiersin.org
Introduction Post-stroke depression (PSD) is the most common emotional problem following
a stroke, which requires early diagnosis to improve the prognosis. Gut microbiota plays …

The regulatory effects of fucoidan and laminarin on functional dyspepsia mice induced by loperamide

T Liu, M Zhang, IM Asif, Y Wu, B Li, L Wang - Food & Function, 2023 - pubs.rsc.org
Gastrointestinal dysmotility is a common cause of functional dyspepsia. As two kinds of
polysaccharides derived from brown algae, fucoidan and laminarin possess many …