Alcoholic beverages such as beer, wine and spirits are widely consumed around the world.
However, alcohol and its metabolite acetaldehyde are toxic and harmful to human beings …

Methods Nested case-control studies and cohort studies involving the general population
published prior to July 2019 were searched. In total, 28 publications (31 cohorts) with 4,899 …

Background Heavy drinking was well associated with an increased risk of hepatocellular
carcinoma (HCC), whereas the effect of low-to-moderate drinking on HCC remains under …

Nonalcoholic beverages are usually consumed accompanying alcoholic drinks, and their
effects on alcohol metabolism are unclear in vivo. In this study, the effects of 20 nonalcoholic …

Glutathione (GSH) is the most abundant non-protein thiol, attaining cellular concentrations in
the millimolar range. GSH functions to protect cells against endogenous and exogenous …

Heavy alcohol intake induces a wide spectrum of liver diseases ranging from steatosis,
steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Although alcohol …

Abstract Background & Aims Increasingly populations are both overweight/obese and
consume alcohol. The risk of liver disease from the combination of these factors is unclear …

Background Alcohol is an established risk factor for several cancers, but modest alcohol-
cancer associations may be missed because of measurement error in self-reported …

Dietary intake of one-carbon metabolism-related nutrients has been linked to cancer-related
outcomes, but their effects on hepatocellular carcinoma (HCC) mortality are still unknown …

Deficient intake of micronutrients involved in one‐carbon metabolism (eg, choline,
methionine, vitamin B12 and folic acid) leads to hepatocellular carcinoma (HCC) …