An intact functioning blood–brain barrier (BBB) is fundamental to proper homoeostatic maintenance and perfusion of the central nervous system (CNS). Inflammatory damage to …
R Versele, E Sevin, F Gosselet, L Fenart… - International journal of …, 2022 - mdpi.com
The blood-brain barrier (BBB) is a selective barrier and a functional gatekeeper for the central nervous system (CNS), essential for maintaining brain homeostasis. The BBB is …
RF Keep, AV Andjelkovic, J Xiang… - Journal of Cerebral …, 2018 - journals.sagepub.com
Vascular disruption is the underlying cause of cerebral hemorrhage, including intracerebral, subarachnoid and intraventricular hemorrhage. The disease etiology also involves cerebral …
CL Eastman, R D'Ambrosio, T Ganesh - Neuropharmacology, 2020 - Elsevier
Traumatic brain injury (TBI) is a leading cause of death and disability in young adults worldwide. TBI survival is associated with persistent neuropsychiatric and neurological …
S Yuan, KJ Liu, Z Qi - Brain circulation, 2020 - journals.lww.com
Occludin is a key structural component of the blood–brain barrier (BBB) that has recently become an important focus of research in BBB damages. Many studies have demonstrated …
S Shekhar, MW Cunningham, MR Pabbidi… - European journal of …, 2018 - Elsevier
Ischemic stroke is a devastating and debilitating medical condition with limited therapeutic options. However, accumulating evidence indicates a central role of inflammation in all …
Exacerbated inflammatory response and altered vascular function are hallmarks of dengue disease. Reactive oxygen species (ROS) production has been associated to endothelial …
U Bayraktutan - Pharmacological Research, 2019 - Elsevier
Stroke is classified into two main groups depending on its aetiology; ischaemic stroke and haemorrhagic stroke which successively develop from the occlusion or rupture of an artery …
L Qin, W Huang, X Mo, Y Chen… - Oxidative medicine and …, 2015 - Wiley Online Library
Disrupted blood‐brain barrier (BBB) integrity contributes to cerebral edema during central nervous system infection. The current study explored the mechanism of lipopolysaccharide …