For a long time, scientists have tried to describe disorders just by genetic or environmental
factors. However, the role of epigenetics in human diseases has been considered from a …

Despite the medical advances of the 21st century, the incidence of cancer continues to
increase and the search for a universal cure remains a major health challenge. Our lack of …

Context: Colorectal cancer is one of the most common cancers worldwide. Epigenetic
alterations play an important role in the pathogenesis of the colorectal cancer. Objective …

Background There is increasing evidence indicating an aberrant expression of miRNAs in
colorectal cancer (CRC) development. Growing evidence has suggested that …

Digestive system cancers are the leading cause of cancer-related death worldwide due to
their high morbidity and mortality rates. The current treatment methods include surgical …

Colorectal cancer (CRC) has been designated a major global problem, especially due to its
high prevalence in developed countries. CRC mostly occurs sporadically (75%-80%), and …

Colorectal cancer (CRC) is the leading cause of cancer death worldwide. A crucial process
that initiates and progresses CRC is various epigenetic and genetic changes occurring in …

Aberrant DNA methylation, which can be detected in circulating cell-free DNA (cfDNA), is
one of the major epigenetic alterations in hepatocellular carcinoma (HCC). UBE2Q1, a …

Background Colorectal cancer (CRC) is one the leading causes of cancer related deaths
among Iranians. Despite the various progresses in new therapeutic methods, it has still a …

We explored differences in the DNA methylation statuses of PSMA6, PSMB5, HIF1A, and
KEAP1 gene promoter regions in patients with type 1 diabetes and different diabetic …