Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Stem cell therapy is a promising strategy for cartilage tissue engineering, and cell
transplantation using polymeric scaffolds has recently gained attention. Herein, we …

Soft tissue defects are a common clinical challenge mostly caused by trauma, congenital
anomalies and oncological surgery. Current soft tissue reconstruction options include …

Mesenchymal stem cells (MSCs) are promising candidates for bone regeneration therapies
due to their plasticity and easiness of sourcing. MSC-based treatments are generally …

Inspired by the extracellular matrix (ECM), biomaterials have emerged as promising
strategies in the biomedical research and engineering domain, offering unique …

In this study, we fabricated a novel multilayer polyvinyl alcohol (PVA)/alginate sulfate (ALG-
S) nanofiber/decellularized Wharton's Jelly ECM (d-ECM) composite for tympanic …

Drug-induced hepatotoxicity is a leading cause of clinical trial withdrawal. Therefore, in vitro
modeling the hepatic behavior and functionalities is not only crucial to better understand …

BACKGROUND Immunosuppression has undoubtedly raised the overall positive outcomes
in the post-operative management of solid organ transplantation. However, long-term …

The aim of this study was to verify the applicability of high-concentration collagen-based
bioink with MSC (ADSC) and decellularized ECM granules for the formation of cartilage …