The major role of biomolecules in treatment of different diseases has been proven by
several studies. However, the main drawback in successful treatment by these molecules is …

The review deals with the use of chitosan and its derivatives as vectors for delivery of nucleic
acids in gene therapy. Factors influencing the transfection efficiency of chitosan-based …

The existence of blood–brain barrier (BBB) greatly hindered the penetration and
accumulation of chemotherapeutics into glioblastoma (GBM), accompany with poor …

Background Reactive oxygen species (ROS)-responsive drug delivery systems (DDSs) are
potential tools to minimize the side effects and substantially enhance the therapeutic efficacy …

Purpose Chemotherapy mediated by Reactive oxygen species (ROS)-responsive drug
delivery systems can potentially mitigate the toxic side effects of chemotherapeutic drugs …

Endometriosis is a common gynecological disease with a lack of effective clinical treatment.
Current therapy often results in endometriosis pain recurrence and serious side effects …

Cancer-related immunosuppression is one of the most challenging aspects of cancer
therapy, being one of the principal causes of disease relapse. Most recent …

Chemotherapy is still one of the major approaches in triple-negative breast cancer (TNBC)
treatment. The development of new formulations for classic chemotherapeutic drugs remains …

The development of advanced gene delivery carriers with stimuli-responsive release
manner for tumor therapeutics is desirable, since they can exclusively release the …

γ-Poly-glutamic acid (γ-PGA) is a naturally occurring homo-polyamide produced by various
strains of Bacillus. As a biopolymer substance, γ-PGA possesses a few predominant …