Polysaccharide-based nanomedicines targeting lung cancer

AA Bhat, G Gupta, KS Alharbi, O Afzal, ASA Altamimi… - Pharmaceutics, 2022 - mdpi.com
A primary illness that accounts for a significant portion of fatalities worldwide is cancer.
Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer …

Orodispersible films: current innovations and emerging trends

S Jacob, SHS Boddu, R Bhandare, SS Ahmad, AB Nair - Pharmaceutics, 2023 - mdpi.com
Orodispersible films (ODFs) are thin, mechanically strong, and flexible polymeric films that
are designed to dissolve or disintegrate rapidly in the oral cavity for local and/or systemic …

Empagliflozin: a potential anticancer drug

W Wu, Y Wang, J Xie, S Fan - Discover Oncology, 2023 - Springer
Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is a highly effective and
well-tolerated antidiabetic drug. In addition to hypoglycemic effects, empagliflozin has many …

Comparative evaluation of metformin and metronidazole release from oral lyophilisates with different methods

VR Timergalieva, CGM Gennari, F Cilurzo… - Scientia …, 2023 - mdpi.com
The aim of this study is to compare three different dissolution methods to assess the drug
release from oral lyophilisates, based on interpolyelectrolyte complexes (IPECs). IPECs …

Weaponizing chitosan and its derivatives in the battle against lung cancer

H Amin, IM Ibrahim, EHM Hassanein - International Journal of Biological …, 2024 - Elsevier
Lung cancer (LC) is a crisis of catastrophic proportions. It is a global problem and urgently
requires a solution. The classic chemo drugs are lagging behind as they lack selectivity …

Nanoparticles with SGLT2 inhibitory activity: Possible benefits and future

H Yaribeygi, M Maleki, T Jamialahmadi… - Diabetes & Metabolic …, 2023 - Elsevier
Aim Nano-drug delivery is a rapidly growing approach in medicine that helps design and
develop newer forms of drugs with more efficacy and lower adverse effects. Sodium-glucose …

Harnessing polyelectrolyte complexes for precision cancer targeting: a comprehensive review

BG Prajapati, JB Sharma, S Sharma, ND Trivedi… - Medical Oncology, 2024 - Springer
Polyelectrolytes represent a unique class of polymers abundant in ionizable functional
groups. In a solution, ionized polyelectrolytes can intricately bond with oppositely charged …

Oral Patch/Film for Drug Delivery—Current Status and Future Prospects

Y Yan, W Yan, S Wu, H Zhao, Q Chen, J Wang - Biopolymers, 2024 - Wiley Online Library
In recent years, there has been extensive research into drug delivery systems aimed at
enhancing drug utilization while minimizing drug toxicities. Among these systems, oral …

Future perspectives, challenges, and opportunities of ionotropic cross-linking of biopolymers in drug delivery

VR Askari, VB Rahimi, VT Khorrami, MR Fadaei… - Ionotropic Cross-Linking …, 2024 - Elsevier
Ionotropically cross-linking is considered one of the simplest and lowest-cost methods for
gelation in biopolymers. In one approach he crosslinked polymers could load drug …

Nanomedicine in the Treatment of Metabolic Diseases

SH Kamran - Nanomedicine in Treatment of Diseases, 2024 - Springer
Nanotechnology employed in drug development has led to the origination of enhanced drug
delivery systems targeted for the mitigation of metabolic diseases. Metabolic diseases …