Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibroproliferative
alterations of the microvasculature leading to fibrosis and loss of function of the skin and …

Pediatric short bowel syndrome (SBS) is a serious condition which occurs in children with
congenital or acquired reduction in length of the small intestine. SBS results in excessive …

Home parenteral nutrition (HPN) was introduced as a treatment modality in the early 1970s
primarily for the treatment of chronic intestinal failure in patients with benign disease. The …

Undernutrition as well as specific nutrient deficiencies has been described in patients with
Crohn's disease (CD), ulcerative colitis (UC) and short bowel syndrome. In the latter, water …

Background Home parenteral nutrition (HPN) is the standard treatment for severe intestinal
failure in the United Kingdom. Aim To review long‐term survival and ongoing HPN …

Short bowel syndrome (SBS) is defined as loss of bowel mass from surgical resection,
congenital defects, or disease. Intestinal failure (IF) includes the subset of SBS unable to …

Scleroderma (systemic sclerosis) is an autoimmune disease that can affect multiple organ
systems. Gastrointestinal (GI) involvement is the most common organ system involved in …

Background Cobalamin deficiency is commonly associated with chronic enteropathies (CE)
in dogs and current treatment protocols recommend parenteral supplementation. In humans …

Summary Rationale Short Bowel Syndrome (SBS) is the major cause of chronic intestinal
failure (IF) and requires parenteral nutrition (PN). After bowel resection, some patients …

Animal models and archived human biobank tissues are useful resources for research in
disease development, diagnostics and therapeutics. For the preservation of microscopic …