Transient dynamics in a class of mathematical models of epileptic seizures

AA Kapustnikov, MV Sysoeva, IV Sysoev - Communications in Nonlinear …, 2022 - Elsevier
A new approach to modeling transitions to epileptic state and back in the brain
thalamocortical system is proposed. Since no specific mechanism for termination of spike …

Suppression of seizure in childhood absence epilepsy using robust control of deep brain stimulation: a simulation study

E Rouhani, E Jafari, A Akhavan - Scientific Reports, 2023 - nature.com
Deep brain stimulation (DBS) is a promising technique to relieve the symptoms in patients
with intractable seizures. Although the DBS therapy for seizure suppression dates back …

Improving control effects of absence seizures using single-pulse alternately resetting stimulation (SARS) of corticothalamic circuit

D Fan, Y Zheng, Z Yang, Q Wang - Applied Mathematics and Mechanics, 2020 - Springer
Presently, we develop a simplified corticothalamic (SCT) model and propose a single-pulse
alternately resetting stimulation (SARS) with sequentially applying anodic (A,“+”) or cathodic …

The dynamical role of electromagnetic induction in epileptic seizures: a double-edged sword

J Zhao, Q Wang - Nonlinear Dynamics, 2021 - Springer
The important role of electromagnetic induction in neuronal activities has received
considerable attention. However, its connection with epilepsy disease is rarely explored …

Detection of seizure onset in childhood absence epilepsy

M Aud'Hui, A Kachenoura, M Yochum… - Clinical …, 2024 - Elsevier
Objective This study aims to detect the seizure onset, in childhood absence epilepsy, as
early as possible. Indeed, interfering with absence seizures with sensory simulation has …

The critical modulatory role of spiny stellate cells in seizure onset based on dynamic analysis of a neural mass model

S Tabatabaee, F Bahrami, M Janahmadi - Frontiers in Neuroscience, 2021 - frontiersin.org
Growing evidence suggests that excitatory neurons in the brain play a significant role in
seizure generation. Nonetheless, spiny stellate cells are cortical excitatory non-pyramidal …

Model predictive control for seizure suppression based on nonlinear auto-regressive moving-average volterra model

S Chang, X Wei, F Su, C Liu, G Yi… - … on Neural Systems …, 2020 - ieeexplore.ieee.org
This article investigates a closed-loop brain stimulation method based on model predictive
control strategy to suppress epileptic seizures. A neural mass model (NMM), exhibiting the …

Dynamic transitions of epilepsy waveforms induced by astrocyte dysfunction and electrical stimulation

H Zhang, Z Shen, Q Zhao, L Yan, L Du… - Neural Plasticity, 2020 - Wiley Online Library
Experimental studies have shown that astrocytes participate in epilepsy through inducing
the release of glutamate. Meanwhile, considering the disinhibition circuit among inhibitory …

Control and analysis of epilepsy waveforms in a disinhibition model of cortex network

Z Shen, Z Deng, L Du, H Zhang, L Yan, P Xiao - Nonlinear Dynamics, 2021 - Springer
Considering the disinhibition circuit between inhibitory neuronal populations with different
time scales in cortical neural networks, here we propose a novel model to describe the …

Interpretation of seizure dynamics using fuzzy-based neural computational modelling

BP Prathaban, S Rajendran, N Ganeshkumar… - Soft Computing, 2023 - Springer
The epileptic seizures result due to the nonlinear dynamic asynchronization of the brain
waves. The temporal dynamics of the brain waves are usually depicted from long-term EEG …