Prostate cancer is a major cause of disease and mortality among men, and each year 1.6
million men are diagnosed with and 366,000 men die of prostate cancer. In this review, we …

This year marks the 20th anniversary of the discovery of leptin, which has tremendously
stimulated translational obesity research. The discovery of leptin has led to realizations that …

CONTEXT: Obesity and prostate cancer (PCa) affect substantial proportions of Western
society. Mounting evidence, both epidemiologic and mechanistic, for an association …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Purpose To determine whether higher physical activity after prostate cancer (PCa) diagnosis
decreases risk of overall and PCa-specific death. Patients and Methods We evaluated …

Increasing evidence suggested obesity, measured by body mass index (BMI), was
associated with prostate cancer–specific mortality, and its impact on biochemical recurrence …

Overweight and obese men with prostate cancer are at an increased risk of disease
recurrence, exacerbated treatment-related adverse effects, development of obesity-related …

CONTEXT: Metabolic syndrome (MetS), a cluster of several metabolic abnormalities with a
high socioeconomic cost, is considered a worldwide epidemic. Recent epidemiologic and …

Prostate cancer (PCa) metabolism appears to be unique in comparison with other types of
solid cancers. Normal prostate cells mainly rely on glucose oxidation to provide precursors …

Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …