Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci

X Han, P Gharahkhani, AR Hamel, JS Ong… - Nature …, 2023 - nature.com
Glaucoma, a leading cause of irreversible blindness, is a highly heritable human disease.
Previous genome-wide association studies have identified over 100 loci for the most …

Loss of Sarm1 reduces retinal ganglion cell loss in chronic glaucoma

H Zeng, JE Mayberry, D Wadkins, N Chen… - Acta neuropathologica …, 2024 - Springer
Glaucoma is one of the leading causes of irreversible blindness worldwide and vision loss in
the disease results from the deterioration of retinal ganglion cells (RGC) and their axons …

[HTML][HTML] Association between Heat Shock Protein-Specific T-Cell Counts and Retinal Nerve Fiber Layer Thickness in Patients with Primary Open-Angle Glaucoma

C Saini, S Jiang, J Devlin, L Pan, Y Tang, J Tang… - Ophthalmology …, 2023 - Elsevier
Objective Previous laboratory reports implicate heat shock protein (HSP)–specific T-cell
responses in glaucoma pathogenesis; here, we aimed to provide direct clinical evidence by …

Risks of glaucoma among individuals with psoriasis: a population-based cohort study

SH Li, CY Cheng - Clinical and Experimental Dermatology, 2024 - academic.oup.com
Background Psoriasis is a chronic systemic disorder with ocular involvement. Objectives To
evaluate the risk of glaucoma among patients with psoriasis. Methods Participants in this …

[HTML][HTML] Candidate SNP Markers Significantly Altering the Affinity of the TATA-Binding Protein for the Promoters of Human Genes Associated with Primary Open-Angle …

K Zolotareva, PA Dotsenko, N Podkolodnyy… - International Journal of …, 2024 - mdpi.com
Primary open-angle glaucoma (POAG) is the most common form of glaucoma. This condition
leads to optic nerve degeneration and eventually to blindness. Tobacco smoking, alcohol …

Analysis of glaucoma associated genes in response to inflammation, an examination of a public data set derived from peripheral blood from patients with hepatitis C

JK Player, SM Riordan, RS Duncan… - Clinical …, 2022 - Taylor & Francis
Introduction Glaucoma is the second leading cause of blindness worldwide and despite its
prevalence, there are still many unanswered questions related to its pathogenesis. There is …

Reply to Geoffrion, D.; Harissi-Dagher, M. Comment on" Wróblewska-Czajka et al. Outcomes of Boston Keratoprosthesis Type I Implantation in Poland: A …

E Wróblewska-Czajka, D Dobrowolski… - Journal of Clinical …, 2024 - search.ebscohost.com
The article is a response to a commentary on a study about Boston Keratoprosthesis Type I
implantation in Poland. The authors acknowledge the high incidence of glaucoma in …

Anterior Chamber Washout During Ahmed Valve Glaucoma Surgery Reduces the Incidence of Hypertensive Phase

MM Chang, CD Yang, HQ Ly, DS Minckler… - Journal of …, 2023 - journals.lww.com
Purpose: To characterize the incidence of postoperative HP in patients receiving AC
washout at the time of AGI. Patients and Methods: A total of 24 patients with medically …

[PDF][PDF] Optical Coherence Tomography Interpretation for Glaucoma

M Yadgari - Journal of Ophthalmic and Optometric Sciences, 2021 - journals.sbmu.ac.ir
Structural glaucomatous changes occur more frequently in the earlier stages of glaucoma
than functional defects, so we should give special care to optical coherence tomography …