Glycine metabolism and its alterations in obesity and metabolic diseases

A Alves, A Bassot, AL Bulteau, L Pirola, B Morio - Nutrients, 2019 - mdpi.com
Glycine is the proteinogenic amino-acid of lowest molecular weight, harboring a hydrogen
atom as a side-chain. In addition to being a building-block for proteins, glycine is also …

Inflammation, vitamin B6 and related pathways

PM Ueland, A McCann, Ø Midttun, A Ulvik - Molecular aspects of medicine, 2017 - Elsevier
The active form of vitamin B6, pyridoxal 5′-phosphate (PLP), serves as a co-factor in more
than 150 enzymatic reactions. Plasma PLP has consistently been shown to be low in …

Glycine metabolism in animals and humans: implications for nutrition and health

W Wang, Z Wu, Z Dai, Y Yang, J Wang, G Wu - Amino acids, 2013 - Springer
Glycine is a major amino acid in mammals and other animals. It is synthesized from serine,
threonine, choline, and hydroxyproline via inter-organ metabolism involving primarily the …

Autism spectrum disorder: advances in diagnosis and evaluation

L Zwaigenbaum, M Penner - Bmj, 2018 - bmj.com
Autism spectrum disorder (ASD) has a variety of causes, and its clinical expression is
generally associated with substantial disability throughout the lifespan. Recent advances …

[PDF][PDF] T cells and aging, January 2002 update

G Pawelec, Y Barnett, R Forsey, D Frasca… - Front Biosci, 2002 - researchgate.net
[Frontiers in Bioscience 7, d1056-1183, May 1, 2002] 1056 T CELLS AND AGING,
JANUARY 2002 UPDATE Graham Pawelec1, Yvonne Barnett Page 1 [Frontiers in …

Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass …

A Oberbach, M Blüher, H Wirth, H Till… - Journal of proteome …, 2011 - ACS Publications
Obesity is associated with multiple adverse health effects and a high risk of developing
metabolic and cardiovascular diseases. Therefore, there is a great need to identify …

Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function

TR Ziegler, ME Evans… - Annual review of …, 2003 - annualreviews.org
▪ Abstract Intestinal epithelial cell turnover (proliferation, migration, differentiation, and
apoptosis) and gut barrier functions are dynamic processes that are markedly affected by …

Cysteine, histidine and glycine exhibit anti-inflammatory effects in human coronary arterial endothelial cells

S Hasegawa, T Ichiyama, I Sonaka… - Clinical & …, 2012 - academic.oup.com
The activation of nuclear factor-kappa B (NF-κB) in vascular endothelial cells may be
involved in vascular pathogeneses such as vasculitis or atherosclerosis. Recently, it has …

Pyruvate kinase type M2: a crossroad in the tumor metabolome

S Mazurek, H Grimm, CB Boschek, P Vaupel… - British Journal of …, 2002 - cambridge.org
Cell proliferation is a process that consumes large amounts of energy. A reduction in the
nutrient supply can lead to cell death by ATP depletion, if cell proliferation is not limited. A …

Cellular metabolism of myeloid cells in sepsis

RJW Arts, MS Gresnigt, LAB Joosten… - Journal of Leucocyte …, 2017 - academic.oup.com
In recent years, it has become appreciated that immune cells have different metabolic
profiles depending on their activation status. During sepsis, circulating leukocytes go …