Super-resolution microscopy (SRM) techniques have revolutionized the process of obtaining
images beyond Abbe's diffraction limit (∼ 200 nm) of the light microscopes. It is possible to …

Label-free detection techniques for single particles and molecules play an important role in
basic science, disease diagnostics, and nanomaterial investigations. While fluorescence …

The counting of discrete photobleaching steps in fluorescence microscopy is ideally suited
to study protein complex stoichiometry in situ. The counting range of photobleaching step …

In recent decades, upconversion nanomaterials (UCNMs) have attracted considerable
research interest because of their unique optical properties, such as large anti-Stokes shifts …

Correlation signal processing of optical three-dimensional (x, y, t) data can produce super-
resolution images. The second-order cross-correlation function XC 2 has been documented …

It is well documented that the nanoscale structures within porous microenvironments greatly
impact the diffusion dynamics of molecules. However, how the interaction between the …

Light-induced blinking, an inherent feature of many forms of super-resolution microscopy,
has been linked to transient reduction of the fluorescent cyanine dye used as an imaging …

Small RNAs are non-coding RNAs that play important roles in the lives of both animals and
plants. They are 21-to 24-nt in length and∼ 10 nm in size. Their small size and high diversity …

Single-molecule fluorescence experiments have transformed our understanding of complex
materials and biological systems. Whether single molecules are used to report on their nano …

The level of carcinoembryonic antigen (CEA) in serum has the significant reference value for
early diagnosis and treatment of various cancers. However, the CEA detection still suffers …