Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions

P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …

Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones

EN da Silva Júnior, GAM Jardim, C Jacob… - European Journal of …, 2019 - Elsevier
Naphthoquinones are of key importance in organic synthesis and medicinal chemistry. In the
last few years, various synthetic routes have been developed to prepare bioactive …

Lewis-base-catalyzed asymmetric [3+ 3] annulation reaction of Morita–Baylis–Hillman carbonates: Enantioselective synthesis of spirocyclohexenes

W Yang, W Sun, C Zhang, Q Wang, Z Guo, B Mao… - ACS …, 2017 - ACS Publications
A Lewis-base-catalyzed enantioselective [3+ 3] annulation reaction of Morita–Baylis–
Hillman (MBH) carbonates with α-arylidene pyrazolinones is described, affording the …

Quaternary carbon center forming formal [3+ 3] cycloaddition reaction via bifunctional catalysis: Asymmetric synthesis of spirocyclohexene pyrazolones

JY Liu, J Zhao, JL Zhang, PF Xu - Organic letters, 2017 - ACS Publications
A variety of spirocyclohexene pyrazolones were synthesized in good yields with excellent
stereoselectivities through an asymmetric, intermolecular, quaternary carbon center forming …

Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights

EHG Da Cruz, MA Silvers, GAM Jardim… - European journal of …, 2016 - Elsevier
Abstract Selenium-containing quinone-based 1, 2, 3-triazoles were synthesized using click
chemistry, the copper catalyzed azide-alkyne 1, 3-dipolar cycloaddition, and evaluated …

Catalytic enantioselective flow processes with solid‐supported chiral catalysts

C Rodríguez‐Escrich, MA Pericàs - The Chemical Record, 2019 - Wiley Online Library
Sustainability concerns are the wind in the sails for the development of novel, more selective
catalytic processes. Hence, chiral catalysts play a crucial role in the green production of …

Applications of chiral squaramides: From asymmetric organocatalysis to biologically active compounds

X Han, HB Zhou, C Dong - The Chemical Record, 2016 - Wiley Online Library
This review seeks to provide coverage on the recent advances in chiral squaramide‐
catalyzed asymmetric transformations and their applications in the synthesis of a variety of …

Beyond copper-catalyzed azide-alkyne 1, 3-dipolar cycloaddition: Synthesis and mechanism insights

RS Gomes, GAM Jardim, RL de Carvalho, MH Araujo… - Tetrahedron, 2019 - Elsevier
The current manuscript describes the catalysts in click chemistry reactions, mechanism
insights and use of other metals beyond copper associated with Azide-Alkyne …

Stereocontrolled Construction of Tetrahydropyrano[2,3-c]pyrazole Scaffold via an Organocatalyzed Formal [3 + 3] Annulation

Y Zheng, L Cui, Y Wang, Z Zhou - The Journal of Organic …, 2016 - ACS Publications
A bifunctional squaramide catalyzed enantioselective formal [3+ 3] annulation reaction with
pyrazolin-5-ones and nitroallylic acetates has been developed. Densely substituted …

Catalytic asymmetric reactions and synthesis of quinones

B Hosamani, MF Ribeiro, EN da Silva Júnior… - Organic & …, 2016 - pubs.rsc.org
Asymmetric reactions and the synthesis of various quinones, carried out in the presence of
chiral organocatalysts and metal–ligand complexes, are reviewed here. The role of …