Stereoselective reactions of nitro compounds in the synthesis of natural compound analogs and active pharmaceutical ingredients

AY Sukhorukov, AA Sukhanova, SG Zlotin - Tetrahedron, 2016 - Elsevier
Nitroalkanes and nitroalkenes have been always considered as convenient and readily
available intermediates in organic synthesis, including total synthesis of natural products. 1 …

Marine pharmacology in 2003–4: Marine compounds with anthelmintic antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet …

AMS Mayer, AD Rodríguez, RGS Berlinck… - … and Physiology Part C …, 2007 - Elsevier
The current marine pharmacology review that covers the peer-reviewed literature during
2003 and 2004 is a sequel to the authors' 1998–2002 reviews, and highlights the preclinical …

Total synthesis of norzoanthamine

M Miyashita, M Sasaki, I Hattori, M Sakai, K Tanino - Science, 2004 - science.org
Norzoanthamine, an alkaloid isolated from Zoanthus sp., can suppress the loss of bone
weight and strength in ovariectomized mice. Norzoanthamine derivatives can also strongly …

May the force (field) Be with you: On the importance of conformational searches in the prediction of NMR chemical shifts

C Cuadrado, AH Daranas, AM Sarotti - Marine Drugs, 2022 - mdpi.com
NMR data prediction is increasingly important in structure elucidation. The impact of force
field selection was assessed, along with geometry and energy cutoffs. Based on the …

Antithrombotics from the sea: Polysaccharides and beyond

F Carvalhal, RR Cristelo, DISP Resende, MMM Pinto… - Marine drugs, 2019 - mdpi.com
Marine organisms exhibit some advantages as a renewable source of potential drugs, far
beyond chemotherapics. Particularly, the number of marine natural products with …

The biology and chemistry of the zoanthamine alkaloids

DC Behenna, JL Stockdill… - Angewandte Chemie …, 2008 - Wiley Online Library
Marine natural products have long played an important role in natural products chemistry
and drug discovery. Mirroring the rich variety and complicated interactions of the marine …

Concise Synthesis of Norzoanthamine Enabled by a Set of Photochemical Transformations

Y Sun, X Zhang, F Jiang, M Zhang… - Journal of the American …, 2024 - ACS Publications
Norzoanthamine is a structurally complex polycyclic natural product that expresses a broad
range of biological activities, rendering facile access to it and its analogs of considerable …

Discovery of novel synthetic methodologies and reagents during natural product synthesis in the post-palytoxin era

AM Armaly, YC DePorre, EJ Groso, PS Riehl… - Chemical …, 2015 - ACS Publications
The synthesis of naturally occurring substances has been a central part of synthetic organic
chemistry since the late 19th century. Looking back on 150 years of history, the primary …

Overview of the order Zoantharia (Cnidaria: anthozoa) in Brazil

MEA Santos, MV Kitahara, A Lindner, JD Reimer - Marine Biodiversity, 2016 - Springer
Zoantharia (Hexacorallia) is an order of benthic cnidarians, which are known to play an
important ecological role in many marine ecosystems. Although the order has a …

New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities

T Costas, P Besada, A Piras, L Acevedo… - Bioorganic & medicinal …, 2010 - Elsevier
New 6-substituted and 2, 6-disubstituted pyridazinone derivatives were obtained starting
from easily accessible alkyl furans by using oxidation with singlet oxygen to give 4-methoxy …