Mass spectrometry imaging (MSI) is a developing technique to measure the spatio-temporal
distribution of many biomolecules in tissues. Over the preceding decade, MSI has been …

Metabolomics, along with other “omics” approaches, is rapidly becoming one of the major
approaches aimed at understanding the organization and dynamics of metabolic networks …

The unmet need for highly accurate methods of disease diagnosis poses new challenges for
developments in laboratory medicine. Advances in mass spectrometry (MS)-based disease …

Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …

In the past 15 years, ambient ionization techniques have witnessed a significant incursion
into the field of mass spectrometry imaging, demonstrating their ability to provide …

Ambient mass spectrometry imaging (AMSI) has attracted much attention in recent years. As
a kind of unlabeled molecular imaging technique, AMSI can enable in situ visualization of a …

HIV replication within tissues may increase in response to a reduced exposure to
antiretroviral drugs. Traditional approaches to measuring drug concentrations in tissues are …

A quantitative mass spectrometry imaging (QMSI) technique using infrared matrix-assisted
laser desorption electrospray ionization (IR-MALDESI) is demonstrated for the antiretroviral …

Single-cell metabolomics is expected to deliver fast and dynamic information on cell
function; therefore, it requires rapid analysis of a wide variety of very small quantities of …

Persistent HIV replication within active viral reservoirs may be caused by inadequate
antiretroviral penetration. Here, we used mass spectrometry imaging with infrared matrix …