Human temperature regulation under heat stress in health, disease, and injury

MN Cramer, D Gagnon, O Laitano… - Physiological …, 2022 - journals.physiology.org
1.1. Background During exercise and with exposure to hot climatic conditions, there is
tendency for the human body to store heat and for body temperatures to rise. Changes in …

Heat shock proteins regulatory role in neurodevelopment

DJ Miller, PE Fort - Frontiers in neuroscience, 2018 - frontiersin.org
Heat shock proteins (Hsps) are a large family of molecular chaperones that are well-known
for their roles in protein maturation, re-folding and degradation. While some Hsps are …

Regulation and function of neurogenesis in the adult mammalian hypothalamus

S Yoo, S Blackshaw - Progress in neurobiology, 2018 - Elsevier
Over the past two decades, evidence has accumulated that neurogenesis can occur in both
the juvenile and adult mammalian hypothalamus. Levels of hypothalamic neurogenesis can …

Adult neurogenesis in mammals–a theme with many variations

L Bonfanti, P Peretto - European Journal of Neuroscience, 2011 - Wiley Online Library
Investigations of adult neurogenesis in recent years have revealed numerous differences
among mammalian species, reflecting the remarkable diversity in brain anatomy and …

Intermittent fasting increases adult hippocampal neurogenesis

SH Baik, V Rajeev, DYW Fann, DG Jo… - Brain and …, 2020 - Wiley Online Library
Introduction Intermittent fasting (IF) has been suggested to have neuroprotective effects
through the activation of multiple signaling pathways. Rodents fasted intermittently exhibit …

Emerging new sites for adult neurogenesis in the mammalian brain: a comparative study between the hypothalamus and the classical neurogenic zones

M Migaud, M Batailler, S Segura… - European Journal of …, 2010 - Wiley Online Library
In adult mammalian brain, two main germinative regions located in the subventricular zone
of the lateral ventricle and in the subgranular cell layer of the hippocampal dentate gyrus …

Noncanonical sites of adult neurogenesis in the mammalian brain

DM Feliciano, A Bordey… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Two decades after the discovery that neural stem cells (NSCs) populate some regions of the
mammalian central nervous system (CNS), deep knowledge has been accumulated on their …

Heat acclimation, epigenetics, and cytoprotection memory

M Horowitz - Comprehensive Physiology, 2011 - Wiley Online Library
Heat acclimation is a within‐life phenotypic adaptation to heat. Plasticity of the
thermoregulatory system is crucial for the induction of heat acclimation. In the last two …

Neural progenitor cells and the hypothalamus

EA Makrygianni, GP Chrousos - Cells, 2023 - mdpi.com
Neural progenitor cells (NPCs) are multipotent neural stem cells (NSCs) capable of self-
renewing and differentiating into neurons, astrocytes and oligodendrocytes. In the …

Thermal manipulation during embryogenesis impacts H3K4me3 and H3K27me3 histone marks in chicken hypothalamus

SA David, A Vitorino Carvalho, C Gimonnet… - Frontiers in …, 2019 - frontiersin.org
Changes in gene activity through epigenetic alterations induced by early environmental
challenges during embryogenesis are known to impact the phenotype, health, and disease …