Therapeutic nanoemulsions in ophthalmic drug administration: Concept in formulations and characterization techniques for ocular drug delivery

M Singh, S Bharadwaj, KE Lee, SG Kang - Journal of Controlled Release, 2020 - Elsevier
The eye is the specialized part of the body and is comprised of numerous physiological
ocular barriers that limit the drug absorption at the action site. Regardless of various efforts …

Nanonization strategies for poorly water-soluble drugs

H Chen, C Khemtong, X Yang, X Chang, J Gao - Drug discovery today, 2011 - Elsevier
Poor water solubility for many drugs and drug candidates remains a major obstacle to their
development and clinical application. Conventional formulations to improve solubility suffer …

Nanoemulsions—advances in formulation, characterization and applications in drug delivery

SA Chime, FC Kenechukwu… - … of nanotechnology in drug …, 2014 - books.google.com
An ideal drug delivery system fulfils the objective of maximizing therapeutic effect while
minimizing toxicity. With the progress in time and advances in science and technology …

Electron microscopy of nanoemulsions: An essential tool for characterisation and stability assessment

V Klang, NB Matsko, C Valenta, F Hofer - Micron, 2012 - Elsevier
The characterisation of pharmaceutical formulations by microscopic techniques is essential
to obtain reliable data about the actual morphology of the system. Since the size range of …

Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer

HB Nair, B Sung, VR Yadav, R Kannappan… - Biochemical …, 2010 - Elsevier
Extensive research within the last two decades has revealed that most chronic illnesses,
including cancer, diabetes, and cardiovascular and pulmonary diseases, are mediated …

Formulation and in vitro evaluation of topical nanoemulsion and nanoemulsion-based gels containing daidzein

ABU Kaplan, M Cetin, D Orgul… - Journal of Drug Delivery …, 2019 - Elsevier
Daidzein (DZ) has antioxidant, anti-inflammatory activities and also inhibits the growth of the
cancer cells. The aim of this study is to formulate nanoemulsions (NEs) and nanoemulsion …

Design and development of nanovehicle-based delivery systems for preventive or therapeutic supplementation with flavonoids

G Leonarduzzi, G Testa, B Sottero… - Current medicinal …, 2010 - ingentaconnect.com
To date more than 4000 compounds are recognized to belong to the class of flavonoids.
These natural phenolic drugs are poorly soluble in water and are rapidly degraded and …

Herbal nano-formulations for topical delivery

S Khogta, J Patel, K Barve, V Londhe - Journal of Herbal Medicine, 2020 - Elsevier
The use of herbal medicines has gained popularity throughout the world in recent times.
Often seen as natural alternatives with fewer side-effects than synthetic medicines, these …

Nanoemulsions as potential vehicles for transdermal and dermal delivery of hydrophobic compounds: an overview

F Shakeel, S Shafiq, N Haq, FK Alanazi… - Expert opinion on drug …, 2012 - Taylor & Francis
Introduction: In recent years, nanoemulsions have been investigated as potential drug
delivery vehicles for transdermal and dermal delivery of many compounds especially …

Drug carrier systems for solubility enhancement of BCS class II drugs: a critical review

S Kumar, D Bhargava, A Thakkar… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Poor aqueous solubility impedes a drug's bioavailability and challenges its pharmaceutical
development. Pharmaceutical development of drugs with poor water solubility requires the …