New insights into the machinery of blood digestion by ticks

D Sojka, Z Franta, M Horn, CR Caffrey, M Mareš… - Trends in …, 2013 - cell.com
Blood-protein digestion is a key physiological process providing essential nutrients for ticks
and is a prerequisite for the transmission of tick-borne pathogens. Recently, substantial …

Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity-a review

PB Santiago, CN de Araújo, FN Motta, YR Praça… - Parasites & vectors, 2017 - Springer
Ticks, triatomines, mosquitoes and sand flies comprise a large number of haematophagous
arthropods considered vectors of human infectious diseases. While consuming blood to …

Global identification of peptidase specificity by multiplex substrate profiling

AJ O'donoghue, AA Eroy-Reveles, GM Knudsen… - Nature …, 2012 - nature.com
We developed a simple and rapid multiplex substrate-profiling method to reveal the
substrate specificity of any endo-or exopeptidase using liquid chromatography–tandem …

RNA-seq analyses of the midgut from blood- and serum-fed Ixodes ricinus ticks

J Perner, J Provazník, J Schrenková, V Urbanová… - Scientific reports, 2016 - nature.com
Adult females of the genus Ixodes imbibe blood meals exceeding about 100 times their own
weight within 7‒9 days. During this period, ticks internalise components of host blood by …

Insight Into the Dynamics of the Ixodes ricinus Nymphal Midgut Proteome

T Kozelková, F Dyčka, S Lu, V Urbanová… - Molecular & Cellular …, 2023 - ASBMB
Ticks are ectoparasites that feed on blood and have an impressive ability to consume and
process enormous amounts of host blood, allowing extremely long periods of starvation …

Integration of Ixodes ricinus genome sequencing with transcriptome and proteome annotation of the naïve midgut

WJ Cramaro, D Revets, OE Hunewald, R Sinner… - BMC genomics, 2015 - Springer
Abstract Background In Europe, Ixodes ricinus ticks are the most important vectors of
diseases threatening humans, livestock, wildlife and companion animals. Nevertheless …

Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling

J Vorel, K Cwiklinski, P Roudnický, J Ilgová… - BMC genomics, 2021 - Springer
Background Ectoparasites from the family Diplozoidae (Platyhelminthes, Monogenea)
belong to obligate haematophagous helminths of cyprinid fish. Current knowledge of these …

Lesser protein degradation machinery correlates with higher BM86 tick vaccine efficacy in Rhipicephalus annulatus when compared to Rhipicephalus microplus

M Popara, M Villar, L Mateos-Hernández, IGF de Mera… - Vaccine, 2013 - Elsevier
Infestations with cattle ticks, Rhipicephalus (Boophilus) microplus and Rhipicephalus
annulatus, economically impact cattle production in tropical and subtropical regions of the …

Catalogue of stage-specific transcripts in Ixodes ricinus and their potential functions during the tick life-cycle

P Vechtova, Z Fussy, R Cegan, J Sterba, J Erhart… - Parasites & vectors, 2020 - Springer
Background The castor bean tick Ixodes ricinus is an important vector of several clinically
important diseases, whose prevalence increases with accelerating global climate changes …

Genomic and transcriptomic identification of the cathepsin superfamily in the Mediterranean mussel Mytilus galloprovincialis

A Romero, B Novoa, A Figueras - Developmental & Comparative …, 2022 - Elsevier
Cathepsins are lysosomal enzymes that participate in important physiological processes,
such as development, tissue remodelling, senescence and innate and adaptive immunity …