Background: The application of liquid biopsy analysis utilizing circulating tumor DNA
(ctDNA) has gained prominence as a biomarker in specific cancer types. Nevertheless, the …

Traditional tumor diagnosis methods rely on tissue biopsy, which can be invasive and
unsuitable for long-term monitoring of tumor dynamics. The advent of liquid biopsy has …

Lung cancer is responsible for the death of over a million people worldwide every year. With
its high mortality rate and exponentially growing number of new cases, lung cancer is a …

Objective Circulating tumor DNA assays have robust potential as molecular surveillance
tools. They may also exacerbate patient distress without improving outcomes. We …

Importance In a randomized clinical trial, treatment guided by tumor-informed circulating
tumor (ct) DNA testing reduced adjuvant chemotherapy use without compromising …

Background Studies have shown that the circulating tumor cells (CTCs) play a key role for
invasion and formation of distant metastases in prostate cancer (PCa). However, few CTCs …

As we conclude this Special Issue of 21 published articles dedicated to cell-free DNA
(cfDNA) as a prognostic and predictive biomarker in solid cancers, we find ourselves gazing …

目的: 开展基于克隆进化原理的循环肿瘤DNA 在晚期前列腺癌临床监测中的探索性应用研究.
方法: 纳入2 例临床特征为低前列腺特异性抗原(prostate-specificantigen, PSA) …

Merkel cell carcinoma (MCC) is an aggressive cutaneous cancer that carries a high risk of
metastasis and recurrence. 1 Advanced age and immune suppression significantly increase …

Liquid biopsy (LB) represents a promising strategy for the early diagnosis and treatment of
lung cancer. However, relying solely on single-biomarker immunohistochemistry for …