Inflammatory, metabolic, and genetic mechanisms of vascular calcification

LL Demer, Y Tintut - Arteriosclerosis, thrombosis, and vascular …, 2014 - Am Heart Assoc
This review centers on updating the active research area of vascular calcification. This
pathology underlies substantial cardiovascular morbidity and mortality, through adverse …

Collective cell migration: a physics perspective

V Hakim, P Silberzan - Reports on Progress in Physics, 2017 - iopscience.iop.org
Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …

Cellular chirality arising from the self-organization of the actin cytoskeleton

YH Tee, T Shemesh, V Thiagarajan, RF Hariadi… - Nature cell …, 2015 - nature.com
Cellular mechanisms underlying the development of left–right asymmetry in tissues and
embryos remain obscure. Here, the development of a chiral pattern of actomyosin was …

Spontaneous shear flow in confined cellular nematics

G Duclos, C Blanch-Mercader, V Yashunsky… - Nature physics, 2018 - nature.com
In embryonic development or tumour evolution, cells often migrate collectively within
confining tracks defined by their microenvironment,. In some of these situations, the …

Cell chirality: its origin and roles in left–right asymmetric development

M Inaki, J Liu, K Matsuno - Philosophical Transactions of …, 2016 - royalsocietypublishing.org
An item is chiral if it cannot be superimposed on its mirror image. Most biological molecules
are chiral. The homochirality of amino acids ensures that proteins are chiral, which is …

[HTML][HTML] A unified model for left–right asymmetry? Comparison and synthesis of molecular models of embryonic laterality

LN Vandenberg, M Levin - Developmental biology, 2013 - Elsevier
Understanding how and when the left–right (LR) axis is first established is a fundamental
question in developmental biology. A popular model is that the LR axis is established …

A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality

ES Noël, M Verhoeven, AK Lagendijk… - Nature …, 2013 - nature.com
Breaking left–right symmetry in bilateria is a major event during embryo development that is
required for asymmetric organ position, directional organ looping and lateralized organ …

Synthetic living machines: A new window on life

MR Ebrahimkhani, M Levin - Iscience, 2021 - cell.com
Increased control of biological growth and form is an essential gateway to transformative
medical advances. Repairing of birth defects, restoring lost or damaged organs, normalizing …

Exploration of possible cell chirality using material techniques of surface patterning

X Yao, X Wang, J Ding - Acta Biomaterialia, 2021 - Elsevier
Consistent left-right (LR) asymmetry or chirality is critical for embryonic development and
function maintenance. While chirality on either molecular or organism level has been well …

Effects of microstripe geometry on guided cell migration

X Yao, J Ding - ACS applied materials & interfaces, 2020 - ACS Publications
Cell migration on material surfaces is a fundament issue in the fields of biomaterials, cell
biology, tissue engineering, regenerative medicine, etc. Herein, we aim to guide cell …