Asthma is a complex disease with varied clinical manifestations resulting from the interaction
between environmental and genetic factors. While chronic airway inflammation and …

Hepatocellular carcinoma (HCC) is a solid tumor prone to chemotherapy resistance, and
combined immunotherapy is expected to bring a breakthrough in HCC treatment. However …

Long noncoding RNAs (lncRNAs) possess the potential for therapeutic targeting to treat
many disorders, including cancers. Several RNA-based therapeutics (ASOs and small …

Background: Breast cancer (BC) is the most common malignancy in women with high
heterogeneity. The heterogeneity of cancer cells from different BC subtypes has not been …

Objective This study aimed to explore the heterogeneity of tumor endothelial cells (TECs) in
hepatocellular carcinoma (HCC) and their role in tumor progression, with the goal of …

Based on the joint analysis of multi-omic data and the biological experiments, we
demonstrate that FOXF1 inhibits invasion and metastasis of lung adenocarcinoma cells and …

Background Colorectal cancer (CRC) is a significant public health issue, ranking as one of
the predominant cancer types globally in terms of incidence. Intriguingly, Arenobufagin …

Background: Helicobacter pylori (HP) is associated with the development of various stomach
diseases, one of the major risk factors for stomach adenocarcinoma (STAD). Methods: The …

Objective Inhibitors of cyclin‐dependent kinase 4 and 6 (CDK4/6) are targeted therapeutic
drugs for breast cancer treatment. The mechanism of resistance to these inhibitors requires …

Nicotinamide adenine dinucleotide (NAD+) plays an essential role in cellular metabolism,
mitochondrial homeostasis, inflammation, and senescence. However, the role of NAD+ …